TICH-3 trial
Tranexamic acid for IntraCerebral Haemorrhage 3


ISRCTN 97695350
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Room S/D2108, Stroke Trials Unit
School of Medicine, University of Nottingham
Queen's Medical Centre, Derby Road
Nottingham NG7 2UH, United Kingdom
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  • Serious Adverse Events (SAEs) — we have a legal responsibility to collect all safety events occurring within the first 7 days after randomisation (including SARs/SUSARs/fatal SAEs).
  • Safety events include: venous thromboembolism; ischaemic events (arterial thrombosis at any site, ischaemic stroke, transient ischaemic attack, peripheral artery embolism, myocardial infarction, acute coronary syndrome) and seizures.
  • Please remember that fatal SAEs need to be reported, even if after 7 days - unless death occurred after discharge from hospital.
  • Investigators have a legal responsibility to report applicable SAEs to the chief investigator without delay, within 24 hours.

Latest recruiting hospitals
Royal Infirmary of Edinburgh, Edinburgh, UK
ASST Ovest Milanese, Legnano, Italy
The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
Hospital Queen Elizabeth, Sabah, Malaysia
South West Acute Hospital, County Fermanagh, UK
Queen Elizabeth Hospital Birmingham, Birmingham, UK
Milton Keynes University Hospital, Milton Keynes, UK
Tallaght University Hospital, Dublin, Republic of Ireland
St. George's Hospital, London, UK
Helsinki University Hospital, Helsinki, Finland
Peterborough City Hospital, Peterborough, UK
LTD Pineo Medical Ecosystem, Tbilisi, Georgia
ASST di Mantova, Mantova, Italy
James Cook University Hospital, Middlesbrough, UK
University Hospitals Monkland, Airdrie, UK
 
Average time to randomisation (last 6 months)
# Hours Hospital
4 2.1 Azienda Ospedalieria di Rilievo Nazionale Antonio Cardarelli, Napoli, Italy
28 2.2 Helsinki University Hospital, Helsinki, Finland
2 2.4 Doncaster Royal Infirmary, Doncaster, UK
20 2.4 Bispebjerg Hospital, Copenhagen, Denmark
1 2.4 Peterborough City Hospital, Peterborough, UK
6 2.4 St. George's Hospital, London, UK
2 2.4 Aintree University Hospital, Liverpool, UK
2 2.5 University Hospitals Monkland, Airdrie, UK
2 2.5 Royal United Hospital Bath, Bath, UK
3 2.6 South West Acute Hospital, County Fermanagh, UK
8 2.6 Royal Infirmary of Edinburgh, Edinburgh, UK
11 2.6 LTD Pineo Medical Ecosystem, Tbilisi, Georgia
1 2.6 Princess Royal University Hospital, Orpington, UK
5 2.7 Salford Royal Hospital, Salford, UK
4 2.8 Aberdeen Royal Infirmary, Aberdeen, UK
3 2.8 The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
2 2.8 Northumbria Specialist Emergency Care Hospital, Northumberland, UK
8 2.9 The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
2 2.9 Ninewells Hospital, Dundee, UK
3 2.9 Leicester Royal Infirmary, Leicester, UK
7 2.9 Southampton General Hospital, Southampton, UK
9 2.9 Hôpital Roger Salengro, Lille, France
14 3.0 LEPL The First University Clinic of Tbilisi State, Tbilisi, Georgia
2 3.0 Musgrove Park Hospital, Taunton, UK
15 3.0 UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
2 3.0 Tallaght University Hospital, Dublin, Republic of Ireland
2 3.0 Hospital Tuanku Jaafar, Seremban, Negeri Sembilan, Malaysia
1 3.0 Ipswich Hospital, Ipswich, UK
4 3.0 Hull Royal Infirmary, Hull, UK
9 3.1 ASST Ovest Milanese, Legnano, Italy
3 3.1 Hôpital Foch, Suresnes, France
1 3.1 Fairfield General Hospital, Bury, UK
3 3.1 Southmead Hospital, Bristol, UK
2 3.1 Kent & Canterbury Hospital, Canterbury, Kent, UK
8 3.2 Hospital Queen Elizabeth II, Sabah, Malaysia
6 3.2 Hospital Seberang Jaya, Pulau Pinang, Malaysia
3 3.2 King's College Hospital, London, UK
4 3.2 Victoria Hospital, Kirkcaldy, UK
4 3.2 Leeds General Infirmary, Leeds, UK
1 3.2 Bradford Royal Infirmary, Bradford, UK
3 3.2 Hospital Sultanah Bahiyah, Kedah, Malaysia
4 3.2 Craigavon Area Hospital, Portadown, UK
19 3.3 Hospital Queen Elizabeth, Sabah, Malaysia
11 3.3 Royal London Hospital, London, UK
3 3.3 New Cross Hospital, Wolverhampton, UK
7 3.3 Royal Stoke University Hospital, Stoke-on-Trent, UK
5 3.3 Royal Cornwall Hospital, Cornwall, UK
4 3.3 Hôpital André Mignot, Le Chesnay, France
3 3.4 Charing Cross Hospital, London, UK
6 3.4 Centre Hospitalier Sud Francilien, Paris, France
2 3.4 Sunderland Royal Hospital, Tyne and Wear, UK
3 3.4 Royal Derby Hospital, Derby, UK
4 3.5 Hospital Sultanah Nur Zahirah, Terengganu, Malaysia
1 3.5 Hospital Umum Sarawak, Sarawak, Malaysia
3 3.6 University Hospital of North Durham, Durham, UK
3 3.6 ASST di Mantova, Mantova, Italy
2 3.6 Darent Valley Hospital, Dartford, UK
3 3.6 Royal Preston Hospital, Preston, UK
3 3.6 Watford General Hospital, Watford, UK
3 3.7 Royal Victoria Hospital, Belfast, UK
8 3.7 Hôpital Pierre Paul Riquet, Toulouse, France
1 3.7 Hospital Sultanah Aminah, Johor, Malaysia
1 3.7 Hospital Universiti Sains Malaysia, Kelantan, Malaysia
6 3.7 Addenbrooke's Hospital, Cambridge, UK
7 3.7 Queen Elizabeth Hospital Birmingham, Birmingham, UK
2 3.7 Hospital Tengku Ampuan Rahimah, Selangor, Malaysia
2 3.8 Arrowe Park Hospital, Wirral, UK
4 3.8 Luton and Dunstable University Hospital, Luton, UK
4 3.8 University Hospital of North Tees, Stockton on Tees, UK
4 3.9 Queen's Hospital, Romford, UK
2 3.9 Southend University Hospital, Essex, UK
2 3.9 Northwick Park Hospital, Harrow, UK
3 3.9 Queen's Medical Centre, Nottingham, UK
4 4.0 Yeovil District Hospital, Somerset, UK
2 4.0 Hôpital Jean Minjoz, Besançon, France
1 4.0 Hospital UiTM, Selangor, Malaysia
3 4.1 James Cook University Hospital, Middlesbrough, UK
3 4.1 Countess of Chester Hospital, Chester, UK
2 4.1 Basildon University Hospital, Essex, UK
1 4.1 Hospital Pengajar UPM, Serdang Selangor, Malaysia
3 4.1 Milton Keynes University Hospital, Milton Keynes, UK
2 4.2 Hospital Kuala Lumpur, Kuala Lumpur, Malaysia
1 4.2 Royal Devon and Exeter Hospital, Exeter, UK
2 4.4 King's Mill Hospital, Sutton in Ashfield, UK
1 4.4 York Hospital, York, UK
1 4.6 Royal Hallamshire Hospital, Sheffield, UK
1 4.8 Lincoln County Hospital, Lincoln, UK
1 5.0 Royal Berkshire Hospital, Berkshire, UK
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