TICH-3 trial
Tranexamic acid for IntraCerebral Haemorrhage 3


ISRCTN 97695350
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Room S/D2108, Stroke Trials Unit
School of Medicine, University of Nottingham
Queen's Medical Centre, Derby Road
Nottingham NG7 2UH, United Kingdom
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  • Serious Adverse Events (SAEs) — we have a legal responsibility to collect all safety events occurring within the first 7 days after randomisation (including SARs/SUSARs/fatal SAEs).
  • Safety events include: venous thromboembolism; ischaemic events (arterial thrombosis at any site, ischaemic stroke, transient ischaemic attack, peripheral artery embolism, myocardial infarction, acute coronary syndrome) and seizures.
  • Please remember that fatal SAEs need to be reported, even if after 7 days - unless death occurred after discharge from hospital.
  • Please assess if expected according to SmPC.  Expectedness should only be assessed in events that are thought to be possibly/probably/definitely related to the IMP.
  • Investigators have a legal responsibility to report applicable SAEs to the chief investigator without delay, within 24 hours.

Latest recruiting hospitals
Princess Royal University Hospital, Orpington, UK
The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
Bispebjerg Hospital, Copenhagen, Denmark
Royal Stoke University Hospital, Stoke-on-Trent, UK
Hôpital Pierre Paul Riquet, Toulouse, France
Hospital Universitari Vall d'Hebron, Barcelona, Spain
Hospital UiTM, Selangor, Malaysia
Hôpital Pellegrin Bordeaux, Bordeaux, France
Royal Hallamshire Hospital, Sheffield, UK
St. George's Hospital, London, UK
Hôpital Nord Laennec, Nantes, France
LTD Pineo Medical Ecosystem, Tbilisi, Georgia
Dorset County Hospital, Dorset, UK
Helsinki University Hospital, Helsinki, Finland
Leeds General Infirmary, Leeds, UK
  
Average time to randomisation (last 6 months)
# Hours Hospital
2 1.8 Prince Philip Hospital, Llanelli, UK
1 2.0 Hôpital Jean Minjoz, Besançon, France
1 2.0 Hôpital Foch, Suresnes, France
7 2.1 St. George's Hospital, London, UK
1 2.2 Musgrove Park Hospital, Taunton, UK
1 2.2 Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France
16 2.2 Bispebjerg Hospital, Copenhagen, Denmark
2 2.3 Countess of Chester Hospital, Chester, UK
1 2.3 Royal Victoria Hospital, Belfast, UK
7 2.4 Azienda Ospedalieria di Rilievo Nazionale Antonio Cardarelli, Napoli, Italy
2 2.5 Southend University Hospital, Essex, UK
5 2.5 Hull Royal Infirmary, Hull, UK
3 2.6 Basildon University Hospital, Essex, UK
6 2.6 CHU Lyon, Lyon, France
5 2.6 LTD Pineo Medical Ecosystem, Tbilisi, Georgia
24 2.7 Helsinki University Hospital, Helsinki, Finland
9 2.7 University Hospital of North Durham, Durham, UK
9 2.7 Hospital Queen Elizabeth II, Sabah, Malaysia
13 2.8 ASST Ovest Milanese, Legnano, Italy
3 2.8 Antrim Area Hospital, Antrim, UK
4 2.8 Hospital Sultanah Bahiyah, Kedah, Malaysia
3 2.8 Tallaght University Hospital, Dublin, Republic of Ireland
6 2.9 Royal Infirmary of Edinburgh, Edinburgh, UK
9 2.9 Hospital Universitari Vall d'Hebron, Barcelona, Spain
20 2.9 The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
8 2.9 Hôpital Nord Laennec, Nantes, France
10 2.9 UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
5 3.0 Salford Royal Hospital, Salford, UK
9 3.0 Centre Hospitalier Sud Francilien, Paris, France
2 3.0 Ninewells Hospital, Dundee, UK
4 3.0 Hôpital André Mignot, Le Chesnay, France
3 3.0 York Hospital, York, UK
4 3.1 Queen's Hospital, Romford, UK
2 3.1 Darent Valley Hospital, Dartford, UK
2 3.1 Milton Keynes University Hospital, Milton Keynes, UK
3 3.1 Royal Preston Hospital, Preston, UK
9 3.2 Royal London Hospital, London, UK
6 3.2 LEPL The First University Clinic of Tbilisi State, Tbilisi, Georgia
9 3.2 Charing Cross Hospital, London, UK
6 3.2 New Cross Hospital, Wolverhampton, UK
5 3.2 Kantonsspital St.Gallen, St. Gallen, Switzerland
5 3.2 Aintree University Hospital, Liverpool, UK
7 3.2 Craigavon Area Hospital, Portadown, UK
6 3.2 The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
5 3.2 Queen's Medical Centre, Nottingham, UK
4 3.2 Hôpital Lariboisière, Paris, France
5 3.3 Lincoln County Hospital, Lincoln, UK
3 3.3 Norfolk and Norwich University Hospital, Norwich, UK
6 3.3 Addenbrooke's Hospital, Cambridge, UK
4 3.3 Hôpital Roger Salengro, Lille, France
5 3.3 King's College Hospital, London, UK
3 3.3 Cheltenham General Hospital, Cheltenham, UK
6 3.3 Eastbourne General District Hospital, Eastbourne, UK
8 3.3 Hospital Tuanku Jaafar, Seremban, Negeri Sembilan, Malaysia
5 3.4 Hospital Sultanah Aminah, Johor, Malaysia
4 3.4 Hospital Umum Sarawak, Sarawak, Malaysia
6 3.4 Aberdeen Royal Infirmary, Aberdeen, UK
3 3.4 Hôpital Pellegrin Bordeaux, Bordeaux, France
8 3.4 Hôpital Pierre Paul Riquet, Toulouse, France
1 3.4 South West Acute Hospital, County Fermanagh, UK
10 3.4 Hospital Queen Elizabeth, Sabah, Malaysia
3 3.4 University Hospital of North Tees, Stockton on Tees, UK
4 3.4 ASST di Mantova, Mantova, Italy
5 3.5 CHU Rouen, Rouen, France
2 3.5 Leeds General Infirmary, Leeds, UK
3 3.6 Hospital Tengku Ampuan Rahimah, Selangor, Malaysia
1 3.6 Morriston Hospital, Swansea, UK
1 3.6 Doncaster Royal Infirmary, Doncaster, UK
2 3.6 Leicester Royal Infirmary, Leicester, UK
1 3.6 Derriford Hospital, Plymouth, UK
8 3.6 James Cook University Hospital, Middlesbrough, UK
2 3.6 Arrowe Park Hospital, Wirral, UK
4 3.7 Ipswich Hospital, Ipswich, UK
6 3.7 Hospital Seberang Jaya, Pulau Pinang, Malaysia
2 3.7 Hospital Universiti Sains Malaysia, Kelantan, Malaysia
2 3.7 Queen Elizabeth Hospital Birmingham, Birmingham, UK
5 3.7 Victoria Hospital, Kirkcaldy, UK
2 3.7 CHU Poitiers, Poitiers, France
1 3.7 Royal Derby Hospital, Derby, UK
3 3.8 Southampton General Hospital, Southampton, UK
7 3.8 Royal Stoke University Hospital, Stoke-on-Trent, UK
2 3.9 Dorset County Hospital, Dorset, UK
5 3.9 Southmead Hospital, Bristol, UK
2 4.0 West Suffolk Hospital, Bury St Edmunds, UK
5 4.0 King's Mill Hospital, Sutton in Ashfield, UK
1 4.0 Hospital Kuala Lumpur, Kuala Lumpur, Malaysia
1 4.1 Hospital Pengajar UPM, Serdang Selangor, Malaysia
3 4.2 Royal Hallamshire Hospital, Sheffield, UK
1 4.2 Yeovil District Hospital, Somerset, UK
1 4.3 University Hospital Coventry, Coventry, UK
3 4.4 Northwick Park Hospital, Harrow, UK
3 4.4 Royal Bournemouth Hospital, Bournemouth, UK
1 4.5 Luton and Dunstable University Hospital, Luton, UK
2 4.5 Hospital UiTM, Selangor, Malaysia
1 4.7 Princess Royal University Hospital, Orpington, UK
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