TICH-3 trial
Tranexamic acid for IntraCerebral Haemorrhage 3


ISRCTN 97695350
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Room S/D2108, Stroke Trials Unit
School of Medicine, University of Nottingham
Queen's Medical Centre, Derby Road
Nottingham NG7 2UH, United Kingdom
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  • Serious Adverse Events (SAEs) — we have a legal responsibility to collect all safety events occurring within the first 7 days after randomisation (including SARs/SUSARs/fatal SAEs).
  • Safety events include: venous thromboembolism; ischaemic events (arterial thrombosis at any site, ischaemic stroke, transient ischaemic attack, peripheral artery embolism, myocardial infarction, acute coronary syndrome) and seizures.
  • Please remember that fatal SAEs need to be reported, even if after 7 days - unless death occurred after discharge from hospital.
  • Please assess if expected according to RSI.  Expectedness should only be assessed in events that are thought to be possibly/probably/definitely related to the IMP.
  • Investigators have a legal responsibility to report applicable SAEs to the chief investigator without delay, within 24 hours.

Latest recruiting hospitals
Watford General Hospital, Watford, UK
Morriston Hospital, Swansea, UK
Helsinki University Hospital, Helsinki, Finland
King's College Hospital, London, UK
The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
Aberdeen Royal Infirmary, Aberdeen, UK
New Cross Hospital, Wolverhampton, UK
Royal Preston Hospital, Preston, UK
Hospital Sultanah Aminah, Johor, Malaysia
Aalborg University Hospital, Aalborg, Denmark
Hospital Queen Elizabeth, Sabah, Malaysia
University Hospital Hairmyres, East Kilbride, UK
UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
Hospital Queen Elizabeth II, Sabah, Malaysia
Odense University Hospital, Odense, Denmark
  
Average time to randomisation (last 6 months)
# Hours Hospital
1 0.8 Uppsala University Hospital, Uppsala, Sweden
2 1.9 Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
4 2.2 Aarhus University Hospital, Aarhus, Denmark
28 2.2 Bispebjerg Hospital, Copenhagen, Denmark
20 2.2 Helsinki University Hospital, Helsinki, Finland
4 2.2 Azienda Ospedalieria di Rilievo Nazionale Antonio Cardarelli, Napoli, Italy
1 2.2 Kent & Canterbury Hospital, Canterbury, Kent, UK
1 2.3 Royal United Hospital Bath, Bath, UK
1 2.3 University Hospitals Monkland, Airdrie, UK
1 2.3 Arrowe Park Hospital, Wirral, UK
2 2.5 LTD Pineo Medical Ecosystem, Tbilisi, Georgia
1 2.5 Mater Misericordiae University Hospital, Dublin, Republic of Ireland
4 2.5 Royal Victoria Hospital, Belfast, UK
11 2.5 ASST Ovest Milanese, Legnano, Italy
13 2.6 Hospital Universitari Vall d'Hebron, Barcelona, Spain
5 2.6 Odense University Hospital, Odense, Denmark
6 2.6 Derriford Hospital, Plymouth, UK
8 2.6 St. George's Hospital, London, UK
14 2.6 The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
6 2.7 Aberdeen Royal Infirmary, Aberdeen, UK
1 2.7 Hospital UiTM, Selangor, Malaysia
12 2.7 Hospital Universitari de Girona Dr Josep Trueta, Girona, Spain
2 2.8 Yeovil District Hospital, Somerset, UK
15 2.8 Hospital Universitario de A Coruña, A Coruña, Spain
1 2.8 Sunderland Royal Hospital, Tyne and Wear, UK
4 2.8 Hôpital André Mignot, Le Chesnay, France
7 2.8 Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France
9 2.9 CHU Lyon, Lyon, France
6 3.0 Hôpital Foch, Suresnes, France
4 3.0 Hospital Queen Elizabeth II, Sabah, Malaysia
6 3.0 Royal Preston Hospital, Preston, UK
5 3.1 Cheltenham General Hospital, Cheltenham, UK
1 3.1 Milton Keynes University Hospital, Milton Keynes, UK
10 3.1 LEPL The First University Clinic of Tbilisi State, Tbilisi, Georgia
5 3.1 Eastbourne General District Hospital, Eastbourne, UK
1 3.1 Aalborg University Hospital, Aalborg, Denmark
2 3.1 Whiston Hospital, Merseyside, UK
5 3.1 Royal Stoke University Hospital, Stoke-on-Trent, UK
8 3.1 Norfolk and Norwich University Hospital, Norwich, UK
5 3.1 New Cross Hospital, Wolverhampton, UK
7 3.2 Leicester Royal Infirmary, Leicester, UK
7 3.2 University Hospital of North Durham, Durham, UK
2 3.2 Hospital Seberang Jaya, Pulau Pinang, Malaysia
6 3.2 James Cook University Hospital, Middlesbrough, UK
6 3.2 Royal London Hospital, London, UK
7 3.2 Hôpital Pierre Paul Riquet, Toulouse, France
4 3.2 King's College Hospital, London, UK
9 3.2 Hospital Queen Elizabeth, Sabah, Malaysia
1 3.3 Hôpital Lariboisière, Paris, France
2 3.3 Hospital Kuala Lumpur, Kuala Lumpur, Malaysia
2 3.3 Watford General Hospital, Watford, UK
8 3.3 Presidio Ospedale San Carlo, Milano, Italy
3 3.3 CHU Rouen, Rouen, France
10 3.3 UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
21 3.3 The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
2 3.3 Luton and Dunstable University Hospital, Luton, UK
4 3.3 Craigavon Area Hospital, Portadown, UK
7 3.3 Hôpital Nord Laennec, Nantes, France
3 3.4 Southmead Hospital, Bristol, UK
2 3.4 West Suffolk Hospital, Bury St Edmunds, UK
2 3.4 Azienda USL Toscana Nord Ovest, Massa, Italy
7 3.4 Charing Cross Hospital, London, UK
4 3.4 Centre Hospitalier Sainte‐Anne, Paris, France
1 3.4 Aintree University Hospital, Liverpool, UK
4 3.5 Hôpital Pellegrin Bordeaux, Bordeaux, France
2 3.5 Salford Royal Hospital, Salford, UK
4 3.5 York Hospital, York, UK
3 3.5 Southampton General Hospital, Southampton, UK
2 3.6 Hull Royal Infirmary, Hull, UK
2 3.6 Victoria Hospital, Kirkcaldy, UK
3 3.6 Hôpital Jean Minjoz, Besançon, France
5 3.6 University Hospital of North Tees, Stockton on Tees, UK
6 3.6 Addenbrooke's Hospital, Cambridge, UK
2 3.6 Hôpital Roger Salengro, Lille, France
8 3.6 Centre Hospitalier Sud Francilien, Paris, France
7 3.6 Kantonsspital St.Gallen, St. Gallen, Switzerland
3 3.7 Ninewells Hospital, Dundee, UK
5 3.8 Queen's Medical Centre, Nottingham, UK
2 3.8 Royal Infirmary of Edinburgh, Edinburgh, UK
7 3.8 Ipswich Hospital, Ipswich, UK
1 3.8 Countess of Chester Hospital, Chester, UK
5 3.9 Morriston Hospital, Swansea, UK
3 3.9 Royal Bournemouth Hospital, Bournemouth, UK
3 3.9 Royal Derby Hospital, Derby, UK
2 3.9 Antrim Area Hospital, Antrim, UK
1 4.0 University Hospital Coventry, Coventry, UK
1 4.1 Royal Cornwall Hospital, Cornwall, UK
4 4.1 Hospital Tengku Ampuan Rahimah, Selangor, Malaysia
2 4.2 Queen Elizabeth Hospital Birmingham, Birmingham, UK
2 4.2 Hospital Sultanah Aminah, Johor, Malaysia
1 4.3 University Hospital Hairmyres, East Kilbride, UK
1 4.5 Glan Clwyd Hospital, Denbighshire, UK
1 4.5 Tallaght University Hospital, Dublin, Republic of Ireland
1 4.5 Northwick Park Hospital, Harrow, UK
1 4.6 Peterborough City Hospital, Peterborough, UK
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