TICH-3 trial
Tranexamic acid for IntraCerebral Haemorrhage 3


ISRCTN 97695350
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Room S/D2108, Stroke Trials Unit
School of Medicine, University of Nottingham
Queen's Medical Centre, Derby Road
Nottingham NG7 2UH, United Kingdom
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  • Serious Adverse Events (SAEs) — we have a legal responsibility to collect all safety events occurring within the first 7 days after randomisation (including SARs/SUSARs/fatal SAEs).
  • Safety events include: venous thromboembolism; ischaemic events (arterial thrombosis at any site, ischaemic stroke, transient ischaemic attack, peripheral artery embolism, myocardial infarction, acute coronary syndrome) and seizures.
  • Please remember that fatal SAEs need to be reported, even if after 7 days - unless death occurred after discharge from hospital.
  • Please assess if expected according to RSI.  Expectedness should only be assessed in events that are thought to be possibly/probably/definitely related to the IMP.
  • Investigators have a legal responsibility to report applicable SAEs to the chief investigator without delay, within 24 hours.

Latest recruiting hospitals
Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France
ASST Ovest Milanese, Legnano, Italy
Hospital Queen Elizabeth, Sabah, Malaysia
Helsinki University Hospital, Helsinki, Finland
Royal Preston Hospital, Preston, UK
Aalborg University Hospital, Gistrup, Denmark
Hospital Universitario de A Coruña, A Coruña, Spain
Presidio Ospedale San Carlo, Milano, Italy
King's College Hospital, London, UK
Whiston Hospital, Merseyside, UK
Hospital Seberang Jaya, Pulau Pinang, Malaysia
University Hospital Coventry, Coventry, UK
Royal Infirmary of Edinburgh, Edinburgh, UK
St. George's Hospital, London, UK
Milton Keynes University Hospital, Milton Keynes, UK
  
Average time to randomisation (last 6 months)
# Hours Hospital
5 2.0 Azienda Ospedalieria di Rilievo Nazionale Antonio Cardarelli, Napoli, Italy
19 2.0 Bispebjerg Hospital, Copenhagen, Denmark
1 2.2 Salford Royal Hospital, Salford, UK
2 2.2 Southmead Hospital, Bristol, UK
5 2.3 CHU Lyon, Lyon, France
4 2.3 Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
10 2.3 Aalborg University Hospital, Gistrup, Denmark
8 2.4 Aarhus University Hospital, Aarhus, Denmark
7 2.5 Northumbria Specialist Emergency Care Hospital, Northumberland, UK
15 2.5 Helsinki University Hospital, Helsinki, Finland
2 2.5 Victoria Hospital, Kirkcaldy, UK
1 2.6 Southampton General Hospital, Southampton, UK
1 2.6 Cheltenham General Hospital, Cheltenham, UK
14 2.6 Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France
4 2.6 Hospital UiTM, Selangor, Malaysia
1 2.6 Doncaster Royal Infirmary, Doncaster, UK
8 2.6 The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
17 2.7 Hospital Universitario de A Coruña, A Coruña, Spain
2 2.7 Milton Keynes University Hospital, Milton Keynes, UK
2 2.8 Royal Devon and Exeter Hospital, Exeter, UK
7 2.8 ASST Ovest Milanese, Legnano, Italy
4 2.8 Ipswich Hospital, Ipswich, UK
2 2.8 Hospital Sultanah Aminah, Johor, Malaysia
2 2.8 Leeds General Infirmary, Leeds, UK
3 2.8 King's Mill Hospital, Sutton in Ashfield, UK
3 2.8 Norfolk and Norwich University Hospital, Norwich, UK
5 2.8 Royal Stoke University Hospital, Stoke-on-Trent, UK
1 2.8 York Hospital, York, UK
4 2.9 Whiston Hospital, Merseyside, UK
2 2.9 Hôpital Pierre Paul Riquet, Toulouse, France
3 2.9 Eastbourne General District Hospital, Eastbourne, UK
3 2.9 Royal London Hospital, London, UK
8 2.9 Hospital Queen Elizabeth II, Sabah, Malaysia
5 3.0 James Cook University Hospital, Middlesbrough, UK
3 3.0 Centre Hospitalier Sainte‐Anne, Paris, France
15 3.0 St. George's Hospital, London, UK
2 3.1 Aberdeen Royal Infirmary, Aberdeen, UK
8 3.1 Presidio Ospedale San Carlo, Milano, Italy
3 3.1 Hôpital Nord Laennec, Nantes, France
2 3.1 Royal Derby Hospital, Derby, UK
6 3.1 King's College Hospital, London, UK
8 3.1 Aintree University Hospital, Liverpool, UK
4 3.1 Hospital Seberang Jaya, Pulau Pinang, Malaysia
2 3.1 Hôpital Foch, Suresnes, France
4 3.2 Hull Royal Infirmary, Hull, UK
4 3.2 Charing Cross Hospital, London, UK
3 3.2 Addenbrooke's Hospital, Cambridge, UK
7 3.2 Hospital Universitari Vall d'Hebron, Barcelona, Spain
2 3.2 Royal Preston Hospital, Preston, UK
5 3.2 Odense University Hospital, Odense, Denmark
1 3.3 University Hospital Hairmyres, East Kilbride, UK
3 3.3 Leicester Royal Infirmary, Leicester, UK
4 3.3 Hospital Tengku Ampuan Rahimah, Selangor, Malaysia
20 3.3 Hospital Queen Elizabeth, Sabah, Malaysia
5 3.3 Hospital Universitari de Girona Dr Josep Trueta, Girona, Spain
2 3.3 Hôpital Lariboisière, Paris, France
4 3.3 Hôpital Pellegrin Bordeaux, Bordeaux, France
1 3.3 Hospital Pengajar UPM, Serdang Selangor, Malaysia
14 3.3 The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
1 3.3 University Hospital Coventry, Coventry, UK
3 3.4 Kent & Canterbury Hospital, Canterbury, Kent, UK
4 3.4 CHU Rouen, Rouen, France
1 3.4 Morriston Hospital, Swansea, UK
1 3.4 Royal Cornwall Hospital, Cornwall, UK
2 3.4 Royal Bournemouth Hospital, Bournemouth, UK
5 3.5 Hôpital André Mignot, Le Chesnay, France
1 3.5 Rigshospitalet, Copenhagen, Denmark
5 3.5 Queen's Medical Centre, Nottingham, UK
10 3.6 Hospital Sultanah Bahiyah, Kedah, Malaysia
4 3.6 Centre Hospitalier Sud Francilien, Paris, France
2 3.6 Peterborough City Hospital, Peterborough, UK
4 3.7 University Hospital, Cardiff, UK
3 3.7 Watford General Hospital, Watford, UK
1 3.7 Queen's Hospital, Romford, UK
2 3.7 University Hospital of North Durham, Durham, UK
1 3.8 Hospital Tuanku Jaafar, Seremban, Negeri Sembilan, Malaysia
2 3.8 Derriford Hospital, Plymouth, UK
2 3.8 Lincoln County Hospital, Lincoln, UK
2 3.8 Glan Clwyd Hospital, Denbighshire, UK
1 3.8 Ninewells Hospital, Dundee, UK
2 3.9 Basildon University Hospital, Essex, UK
8 4.0 UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
4 4.0 New Cross Hospital, Wolverhampton, UK
2 4.0 Craigavon Area Hospital, Portadown, UK
1 4.0 Royal United Hospital Bath, Bath, UK
2 4.0 West Suffolk Hospital, Bury St Edmunds, UK
1 4.1 Hôpital Jean Minjoz, Besançon, France
2 4.2 University Hospitals Monkland, Airdrie, UK
2 4.3 Fairfield General Hospital, Bury, UK
1 4.3 Yeovil District Hospital, Somerset, UK
1 4.5 Bradford Royal Infirmary, Bradford, UK
10 5.8 Kantonsspital St.Gallen, St. Gallen, Switzerland
5 6.7 Royal Infirmary of Edinburgh, Edinburgh, UK
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