TICH-3 trial
Tranexamic acid for IntraCerebral Haemorrhage 3


ISRCTN 97695350
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Room S/D2108, Stroke Trials Unit
School of Medicine, University of Nottingham
Queen's Medical Centre, Derby Road
Nottingham NG7 2UH, United Kingdom
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  • Serious Adverse Events (SAEs) — we have a legal responsibility to collect all safety events occurring within the first 7 days after randomisation (including SARs/SUSARs/fatal SAEs).
  • Safety events include: venous thromboembolism; ischaemic events (arterial thrombosis at any site, ischaemic stroke, transient ischaemic attack, peripheral artery embolism, myocardial infarction, acute coronary syndrome) and seizures.
  • Please remember that fatal SAEs need to be reported, even if after 7 days - unless death occurred after discharge from hospital.
  • Please assess if expected according to SmPC.  Expectedness should only be assessed in events that are thought to be possibly/probably/definitely related to the IMP.
  • Investigators have a legal responsibility to report applicable SAEs to the chief investigator without delay, within 24 hours.

Latest recruiting hospitals
Queen's Medical Centre, Nottingham, UK
Helsinki University Hospital, Helsinki, Finland
James Cook University Hospital, Middlesbrough, UK
Morriston Hospital, Swansea, UK
Hospital Universitari de Girona Dr Josep Trueta, Girona, Spain
The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
Ipswich Hospital, Ipswich, UK
UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
Cheltenham General Hospital, Cheltenham, UK
Centre Hospitalier Sud Francilien, Paris, France
Hospital Universitario de A Coruña, A Coruña, Spain
Derriford Hospital, Plymouth, UK
Uppsala University Hospital, Uppsala, Sweden
Bispebjerg Hospital, Copenhagen, Denmark
The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
  
Average time to randomisation (last 6 months)
# Hours Hospital
1 0.8 Uppsala University Hospital, Uppsala, Sweden
2 1.9 Odense University Hospital, Odense, Denmark
2 1.9 Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
6 2.0 Azienda Ospedalieria di Rilievo Nazionale Antonio Cardarelli, Napoli, Italy
19 2.1 Helsinki University Hospital, Helsinki, Finland
5 2.1 Aarhus University Hospital, Aarhus, Denmark
26 2.2 Bispebjerg Hospital, Copenhagen, Denmark
1 2.2 Kent & Canterbury Hospital, Canterbury, Kent, UK
1 2.3 University Hospitals Monkland, Airdrie, UK
1 2.3 ASST di Mantova, Mantova, Italy
1 2.3 Whiston Hospital, Merseyside, UK
1 2.3 Arrowe Park Hospital, Wirral, UK
14 2.5 Hospital Universitari Vall d'Hebron, Barcelona, Spain
1 2.5 Mater Misericordiae University Hospital, Dublin, Republic of Ireland
5 2.6 LTD Pineo Medical Ecosystem, Tbilisi, Georgia
12 2.6 ASST Ovest Milanese, Legnano, Italy
14 2.6 The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
5 2.7 Hôpital Foch, Suresnes, France
1 2.7 Hospital UiTM, Selangor, Malaysia
3 2.7 Royal Stoke University Hospital, Stoke-on-Trent, UK
8 2.7 St. George's Hospital, London, UK
3 2.8 Royal Victoria Hospital, Belfast, UK
2 2.8 Yeovil District Hospital, Somerset, UK
10 2.8 Hospital Universitari de Girona Dr Josep Trueta, Girona, Spain
1 2.8 Sunderland Royal Hospital, Tyne and Wear, UK
3 2.8 Aberdeen Royal Infirmary, Aberdeen, UK
9 2.8 CHU Lyon, Lyon, France
7 2.8 Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France
7 2.9 Derriford Hospital, Plymouth, UK
16 3.0 Hospital Universitario de A Coruña, A Coruña, Spain
2 3.0 Royal United Hospital Bath, Bath, UK
5 3.0 Hôpital André Mignot, Le Chesnay, France
12 3.1 LEPL The First University Clinic of Tbilisi State, Tbilisi, Georgia
1 3.1 Doncaster Royal Infirmary, Doncaster, UK
1 3.1 Milton Keynes University Hospital, Milton Keynes, UK
6 3.1 Craigavon Area Hospital, Portadown, UK
7 3.2 Presidio Ospedale San Carlo, Milano, Italy
7 3.2 Leicester Royal Infirmary, Leicester, UK
5 3.2 Cheltenham General Hospital, Cheltenham, UK
7 3.2 University Hospital of North Durham, Durham, UK
2 3.2 Hospital Seberang Jaya, Pulau Pinang, Malaysia
1 3.2 Hull Royal Infirmary, Hull, UK
6 3.2 Hôpital Pierre Paul Riquet, Toulouse, France
5 3.2 Hospital Queen Elizabeth, Sabah, Malaysia
4 3.2 CHU Rouen, Rouen, France
4 3.2 Victoria Hospital, Kirkcaldy, UK
3 3.2 Royal Infirmary of Edinburgh, Edinburgh, UK
8 3.2 Royal London Hospital, London, UK
1 3.3 Hôpital Lariboisière, Paris, France
2 3.3 Hospital Kuala Lumpur, Kuala Lumpur, Malaysia
20 3.3 The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
2 3.3 Luton and Dunstable University Hospital, Luton, UK
6 3.3 Hôpital Nord Laennec, Nantes, France
4 3.3 Eastbourne General District Hospital, Eastbourne, UK
4 3.3 New Cross Hospital, Wolverhampton, UK
6 3.3 Addenbrooke's Hospital, Cambridge, UK
2 3.3 King's College Hospital, London, UK
8 3.3 Charing Cross Hospital, London, UK
2 3.4 West Suffolk Hospital, Bury St Edmunds, UK
7 3.4 UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
6 3.4 Norfolk and Norwich University Hospital, Norwich, UK
2 3.4 Azienda USL Toscana Nord Ovest, Massa, Italy
3 3.4 Southmead Hospital, Bristol, UK
4 3.4 Centre Hospitalier Sainte‐Anne, Paris, France
5 3.4 York Hospital, York, UK
3 3.4 Royal Preston Hospital, Preston, UK
6 3.4 James Cook University Hospital, Middlesbrough, UK
5 3.5 Aintree University Hospital, Liverpool, UK
4 3.5 Hôpital Pellegrin Bordeaux, Bordeaux, France
1 3.5 Watford General Hospital, Watford, UK
2 3.5 Hospital Queen Elizabeth II, Sabah, Malaysia
2 3.5 Salford Royal Hospital, Salford, UK
3 3.5 Southampton General Hospital, Southampton, UK
9 3.6 Centre Hospitalier Sud Francilien, Paris, France
5 3.6 University Hospital of North Tees, Stockton on Tees, UK
2 3.6 Hôpital Roger Salengro, Lille, France
4 3.6 Hôpital Jean Minjoz, Besançon, France
5 3.6 Morriston Hospital, Swansea, UK
3 3.7 Ninewells Hospital, Dundee, UK
6 3.8 Kantonsspital St.Gallen, St. Gallen, Switzerland
5 3.8 Queen's Medical Centre, Nottingham, UK
1 3.8 Countess of Chester Hospital, Chester, UK
5 3.9 Ipswich Hospital, Ipswich, UK
3 3.9 Royal Bournemouth Hospital, Bournemouth, UK
3 3.9 Royal Derby Hospital, Derby, UK
2 3.9 Antrim Area Hospital, Antrim, UK
1 4.0 University Hospital Coventry, Coventry, UK
1 4.1 Queen Elizabeth Hospital Birmingham, Birmingham, UK
2 4.1 Royal Cornwall Hospital, Cornwall, UK
3 4.4 Hospital Tengku Ampuan Rahimah, Selangor, Malaysia
1 4.5 Northwick Park Hospital, Harrow, UK
1 4.6 Peterborough City Hospital, Peterborough, UK
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