TICH-3 trial
Tranexamic acid for IntraCerebral Haemorrhage 3


ISRCTN 97695350
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Room S/D2108, Stroke Trials Unit
School of Medicine, University of Nottingham
Queen's Medical Centre, Derby Road
Nottingham NG7 2UH, United Kingdom
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  • Serious Adverse Events (SAEs) — we have a legal responsibility to collect all safety events occurring within the first 7 days after randomisation (including SARs/SUSARs/fatal SAEs).
  • Safety events include: venous thromboembolism; ischaemic events (arterial thrombosis at any site, ischaemic stroke, transient ischaemic attack, peripheral artery embolism, myocardial infarction, acute coronary syndrome) and seizures.
  • Please remember that fatal SAEs need to be reported, even if after 7 days - unless death occurred after discharge from hospital.
  • Please assess if expected according to RSI.  Expectedness should only be assessed in events that are thought to be possibly/probably/definitely related to the IMP.
  • Investigators have a legal responsibility to report applicable SAEs to the chief investigator without delay, within 24 hours.

Latest recruiting hospitals
Hospital Universitario de A Coruña, A Coruña, Spain
Addenbrooke's Hospital, Cambridge, UK
The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
Watford General Hospital, Watford, UK
Presidio Ospedale San Carlo, Milano, Italy
Ipswich Hospital, Ipswich, UK
Aalborg University Hospital, Gistrup, Denmark
Bispebjerg Hospital, Copenhagen, Denmark
Centre Hospitalier Sainte‐Anne, Paris, France
Fairfield General Hospital, Bury, UK
Aberdeen Royal Infirmary, Aberdeen, UK
Royal Derby Hospital, Derby, UK
Aarhus University Hospital, Aarhus, Denmark
Hospital UiTM, Selangor, Malaysia
Hôpital André Mignot, Le Chesnay, France
  
Average time to randomisation (last 6 months)
# Hours Hospital
5 2.0 Azienda Ospedalieria di Rilievo Nazionale Antonio Cardarelli, Napoli, Italy
1 2.0 Azienda USL Toscana Nord Ovest, Massa, Italy
2 2.1 Milton Keynes University Hospital, Milton Keynes, UK
19 2.1 Bispebjerg Hospital, Copenhagen, Denmark
1 2.2 Salford Royal Hospital, Salford, UK
7 2.2 Aalborg University Hospital, Gistrup, Denmark
4 2.3 Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
9 2.4 Aarhus University Hospital, Aarhus, Denmark
14 2.4 Helsinki University Hospital, Helsinki, Finland
2 2.4 Royal Victoria Hospital, Belfast, UK
1 2.5 Victoria Hospital, Kirkcaldy, UK
8 2.6 Northumbria Specialist Emergency Care Hospital, Northumberland, UK
1 2.6 Southampton General Hospital, Southampton, UK
5 2.6 CHU Lyon, Lyon, France
16 2.6 Hospital Universitario de A Coruña, A Coruña, Spain
7 2.6 ASST Ovest Milanese, Legnano, Italy
4 2.6 Hospital UiTM, Selangor, Malaysia
1 2.6 Doncaster Royal Infirmary, Doncaster, UK
10 2.6 The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
12 2.7 Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France
3 2.7 Leeds General Infirmary, Leeds, UK
3 2.7 Hôpital Foch, Suresnes, France
4 2.8 Ipswich Hospital, Ipswich, UK
2 2.8 Hospital Sultanah Aminah, Johor, Malaysia
3 2.8 King's Mill Hospital, Sutton in Ashfield, UK
3 2.8 Norfolk and Norwich University Hospital, Norwich, UK
6 2.9 Hospital Universitari Vall d'Hebron, Barcelona, Spain
3 2.9 Royal Infirmary of Edinburgh, Edinburgh, UK
4 2.9 Royal Stoke University Hospital, Stoke-on-Trent, UK
4 2.9 Eastbourne General District Hospital, Eastbourne, UK
3 2.9 Southmead Hospital, Bristol, UK
3 2.9 Royal London Hospital, London, UK
2 3.0 Rigshospitalet, Copenhagen, Denmark
4 3.0 Leicester Royal Infirmary, Leicester, UK
7 3.0 Presidio Ospedale San Carlo, Milano, Italy
5 3.0 Hôpital Nord Laennec, Nantes, France
5 3.0 James Cook University Hospital, Middlesbrough, UK
3 3.0 Whiston Hospital, Merseyside, UK
2 3.1 Royal Derby Hospital, Derby, UK
8 3.1 Aintree University Hospital, Liverpool, UK
2 3.1 York Hospital, York, UK
12 3.1 St. George's Hospital, London, UK
4 3.1 Hôpital Pierre Paul Riquet, Toulouse, France
5 3.2 King's College Hospital, London, UK
4 3.2 Charing Cross Hospital, London, UK
4 3.2 Kent & Canterbury Hospital, Canterbury, Kent, UK
3 3.2 Addenbrooke's Hospital, Cambridge, UK
5 3.2 Hull Royal Infirmary, Hull, UK
7 3.2 Hospital Queen Elizabeth II, Sabah, Malaysia
2 3.2 Centre Hospitalier Sainte‐Anne, Paris, France
6 3.2 Hospital Universitari de Girona Dr Josep Trueta, Girona, Spain
14 3.2 The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
4 3.3 Hospital Tengku Ampuan Rahimah, Selangor, Malaysia
1 3.3 University Hospital Hairmyres, East Kilbride, UK
1 3.3 Royal Devon and Exeter Hospital, Exeter, UK
2 3.3 Hôpital Lariboisière, Paris, France
23 3.3 Hospital Queen Elizabeth, Sabah, Malaysia
1 3.3 Hospital Pengajar UPM, Serdang Selangor, Malaysia
8 3.3 Odense University Hospital, Odense, Denmark
4 3.4 CHU Rouen, Rouen, France
1 3.4 Royal Cornwall Hospital, Cornwall, UK
1 3.4 Morriston Hospital, Swansea, UK
2 3.4 Royal Bournemouth Hospital, Bournemouth, UK
4 3.5 Hospital Seberang Jaya, Pulau Pinang, Malaysia
5 3.5 University Hospital, Cardiff, UK
5 3.5 Hôpital Pellegrin Bordeaux, Bordeaux, France
10 3.6 Hospital Sultanah Bahiyah, Kedah, Malaysia
4 3.6 Hôpital André Mignot, Le Chesnay, France
4 3.6 Centre Hospitalier Sud Francilien, Paris, France
2 3.6 Peterborough City Hospital, Peterborough, UK
3 3.6 Aberdeen Royal Infirmary, Aberdeen, UK
3 3.7 Watford General Hospital, Watford, UK
1 3.7 Queen's Hospital, Romford, UK
2 3.7 University Hospital of North Durham, Durham, UK
1 3.8 Hospital Tuanku Jaafar, Seremban, Negeri Sembilan, Malaysia
2 3.8 Derriford Hospital, Plymouth, UK
2 3.8 Lincoln County Hospital, Lincoln, UK
2 3.8 Glan Clwyd Hospital, Denbighshire, UK
1 3.8 Ninewells Hospital, Dundee, UK
10 3.9 UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
6 3.9 Queen's Medical Centre, Nottingham, UK
1 3.9 Antrim Area Hospital, Antrim, UK
1 3.9 University Hospital of North Tees, Stockton on Tees, UK
2 3.9 Basildon University Hospital, Essex, UK
4 4.0 New Cross Hospital, Wolverhampton, UK
2 4.0 Craigavon Area Hospital, Portadown, UK
1 4.0 Royal United Hospital Bath, Bath, UK
3 4.0 West Suffolk Hospital, Bury St Edmunds, UK
1 4.1 ASST di Mantova, Mantova, Italy
1 4.1 Hôpital Jean Minjoz, Besançon, France
2 4.2 University Hospitals Monkland, Airdrie, UK
1 4.2 Royal Preston Hospital, Preston, UK
1 4.3 Cheltenham General Hospital, Cheltenham, UK
2 4.3 Fairfield General Hospital, Bury, UK
1 4.3 Yeovil District Hospital, Somerset, UK
1 4.5 Bradford Royal Infirmary, Bradford, UK
10 5.9 Kantonsspital St.Gallen, St. Gallen, Switzerland
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