TICH-3 trial
Tranexamic acid for IntraCerebral Haemorrhage 3


ISRCTN 97695350
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Room S/D2108, Stroke Trials Unit
School of Medicine, University of Nottingham
Queen's Medical Centre, Derby Road
Nottingham NG7 2UH, United Kingdom
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  • Serious Adverse Events (SAEs) — we have a legal responsibility to collect all safety events occurring within the first 7 days after randomisation (including SARs/SUSARs/fatal SAEs).
  • Safety events include: venous thromboembolism; ischaemic events (arterial thrombosis at any site, ischaemic stroke, transient ischaemic attack, peripheral artery embolism, myocardial infarction, acute coronary syndrome) and seizures.
  • Please remember that fatal SAEs need to be reported, even if after 7 days - unless death occurred after discharge from hospital.
  • Please assess if expected according to RSI.  Expectedness should only be assessed in events that are thought to be possibly/probably/definitely related to the IMP.
  • Investigators have a legal responsibility to report applicable SAEs to the chief investigator without delay, within 24 hours.

Latest recruiting hospitals
University Hospitals Monkland, Airdrie, UK
Leeds General Infirmary, Leeds, UK
Hospital Queen Elizabeth II, Sabah, Malaysia
Whiston Hospital, Merseyside, UK
ASST Ovest Milanese, Legnano, Italy
Queen's Medical Centre, Nottingham, UK
Charing Cross Hospital, London, UK
Kantonsspital St.Gallen, St. Gallen, Switzerland
Peterborough City Hospital, Peterborough, UK
Addenbrooke's Hospital, Cambridge, UK
The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
Aintree University Hospital, Liverpool, UK
Victoria Hospital, Kirkcaldy, UK
CHU Rouen, Rouen, France
Hospital Queen Elizabeth, Sabah, Malaysia
  
Average time to randomisation (last 6 months)
# Hours Hospital
1 0.8 Uppsala University Hospital, Uppsala, Sweden
1 0.8 Hospital UiTM, Selangor, Malaysia
1 1.5 LTD Pineo Medical Ecosystem, Tbilisi, Georgia
1 1.8 Southend University Hospital, Essex, UK
1 2.0 Azienda USL Toscana Nord Ovest, Massa, Italy
4 2.2 Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
5 2.2 Aarhus University Hospital, Aarhus, Denmark
2 2.2 Norfolk and Norwich University Hospital, Norwich, UK
5 2.2 Azienda Ospedalieria di Rilievo Nazionale Antonio Cardarelli, Napoli, Italy
4 2.3 Royal London Hospital, London, UK
5 2.4 Royal Victoria Hospital, Belfast, UK
1 2.4 Milton Keynes University Hospital, Milton Keynes, UK
12 2.4 Aalborg University Hospital, Gistrup, Denmark
1 2.5 Ninewells Hospital, Dundee, UK
19 2.5 Helsinki University Hospital, Helsinki, Finland
13 2.5 ASST Ovest Milanese, Legnano, Italy
5 2.5 Eastbourne General District Hospital, Eastbourne, UK
3 2.6 Lincoln County Hospital, Lincoln, UK
12 2.6 CHU Lyon, Lyon, France
11 2.7 The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
13 2.7 Hospital Universitario de A Coruña, A Coruña, Spain
7 2.7 Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France
3 2.7 Leeds General Infirmary, Leeds, UK
2 2.8 Kent & Canterbury Hospital, Canterbury, Kent, UK
20 2.8 Bispebjerg Hospital, Copenhagen, Denmark
1 2.8 Sunderland Royal Hospital, Tyne and Wear, UK
4 2.8 Leicester Royal Infirmary, Leicester, UK
6 2.9 Aberdeen Royal Infirmary, Aberdeen, UK
9 2.9 Hôpital Nord Laennec, Nantes, France
5 2.9 Southmead Hospital, Bristol, UK
8 3.0 Odense University Hospital, Odense, Denmark
11 3.0 Hospital Universitari Vall d'Hebron, Barcelona, Spain
14 3.0 Hospital Universitari de Girona Dr Josep Trueta, Girona, Spain
6 3.0 Royal Preston Hospital, Preston, UK
1 3.0 Musgrove Park Hospital, Taunton, UK
4 3.0 Whiston Hospital, Merseyside, UK
8 3.0 St. George's Hospital, London, UK
6 3.1 James Cook University Hospital, Middlesbrough, UK
4 3.1 Hôpital Foch, Suresnes, France
4 3.1 Hospital Queen Elizabeth II, Sabah, Malaysia
2 3.2 Aintree University Hospital, Liverpool, UK
4 3.2 New Cross Hospital, Wolverhampton, UK
24 3.2 Hospital Queen Elizabeth, Sabah, Malaysia
6 3.2 Hospital Sultanah Bahiyah, Kedah, Malaysia
7 3.2 Presidio Ospedale San Carlo, Milano, Italy
3 3.2 University Hospitals Monkland, Airdrie, UK
6 3.2 Hospital Sultanah Aminah, Johor, Malaysia
2 3.3 Watford General Hospital, Watford, UK
2 3.3 Royal Infirmary of Edinburgh, Edinburgh, UK
4 3.3 Northumbria Specialist Emergency Care Hospital, Northumberland, UK
5 3.3 Royal Stoke University Hospital, Stoke-on-Trent, UK
1 3.3 Mater Misericordiae University Hospital, Dublin, Republic of Ireland
3 3.3 Rigshospitalet, Copenhagen, Denmark
5 3.3 LEPL The First University Clinic of Tbilisi State, Tbilisi, Georgia
4 3.3 Addenbrooke's Hospital, Cambridge, UK
5 3.3 Victoria Hospital, Kirkcaldy, UK
3 3.3 Hull Royal Infirmary, Hull, UK
1 3.3 Hôpital André Mignot, Le Chesnay, France
4 3.3 Tallaght University Hospital, Dublin, Republic of Ireland
16 3.3 The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
8 3.3 Hôpital Pierre Paul Riquet, Toulouse, France
4 3.4 Cheltenham General Hospital, Cheltenham, UK
6 3.4 Charing Cross Hospital, London, UK
1 3.4 York Hospital, York, UK
18 3.4 UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
2 3.4 King's Mill Hospital, Sutton in Ashfield, UK
2 3.5 Hospital Tuanku Jaafar, Seremban, Negeri Sembilan, Malaysia
6 3.5 Ipswich Hospital, Ipswich, UK
1 3.6 Southampton General Hospital, Southampton, UK
3 3.6 Hôpital Pellegrin Bordeaux, Bordeaux, France
6 3.6 Hospital Tengku Ampuan Rahimah, Selangor, Malaysia
6 3.6 King's College Hospital, London, UK
3 3.6 CHU Rouen, Rouen, France
10 3.7 Centre Hospitalier Sud Francilien, Paris, France
8 3.7 Queen's Medical Centre, Nottingham, UK
1 3.8 Luton and Dunstable University Hospital, Luton, UK
2 3.8 University Hospital Hairmyres, East Kilbride, UK
4 3.8 Morriston Hospital, Swansea, UK
4 3.8 University Hospital, Cardiff, UK
3 3.8 Hôpital Lariboisière, Paris, France
2 3.8 Derriford Hospital, Plymouth, UK
2 3.8 Hôpital Roger Salengro, Lille, France
2 3.9 Royal Derby Hospital, Derby, UK
2 3.9 Hôpital Jean Minjoz, Besançon, France
1 3.9 Antrim Area Hospital, Antrim, UK
1 3.9 University Hospital of North Durham, Durham, UK
3 4.0 University Hospital of North Tees, Stockton on Tees, UK
3 4.0 ASST di Mantova, Mantova, Italy
3 4.0 West Suffolk Hospital, Bury St Edmunds, UK
1 4.0 Royal United Hospital Bath, Bath, UK
1 4.1 Craigavon Area Hospital, Portadown, UK
2 4.2 Glan Clwyd Hospital, Denbighshire, UK
3 4.2 Hospital Seberang Jaya, Pulau Pinang, Malaysia
1 4.3 Queen Elizabeth Hospital Birmingham, Birmingham, UK
1 4.3 Peterborough City Hospital, Peterborough, UK
1 4.5 Bradford Royal Infirmary, Bradford, UK
2 4.5 Salford Royal Hospital, Salford, UK
10 6.0 Kantonsspital St.Gallen, St. Gallen, Switzerland
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