TICH-3 trial
Tranexamic acid for IntraCerebral Haemorrhage 3


ISRCTN 97695350
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Room S/D2108, Stroke Trials Unit
School of Medicine, University of Nottingham
Queen's Medical Centre, Derby Road
Nottingham NG7 2UH, United Kingdom
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  • Serious Adverse Events (SAEs) — we have a legal responsibility to collect all safety events occurring within the first 7 days after randomisation (including SARs/SUSARs/fatal SAEs).
  • Safety events include: venous thromboembolism; ischaemic events (arterial thrombosis at any site, ischaemic stroke, transient ischaemic attack, peripheral artery embolism, myocardial infarction, acute coronary syndrome) and seizures.
  • Please remember that fatal SAEs need to be reported, even if after 7 days - unless death occurred after discharge from hospital.
  • Please assess if expected according to SmPC.  Expectedness should only be assessed in events that are thought to be possibly/probably/definitely related to the IMP.
  • Investigators have a legal responsibility to report applicable SAEs to the chief investigator without delay, within 24 hours.

Latest recruiting hospitals
Hôpital Roger Salengro, Lille, France
Royal Stoke University Hospital, Stoke-on-Trent, UK
Aberdeen Royal Infirmary, Aberdeen, UK
Hospital Tengku Ampuan Rahimah, Selangor, Malaysia
The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
Royal London Hospital, London, UK
University Hospital Coventry, Coventry, UK
ASST Ovest Milanese, Legnano, Italy
LEPL The First University Clinic of Tbilisi State, Tbilisi, Georgia
New Cross Hospital, Wolverhampton, UK
Royal Hallamshire Hospital, Sheffield, UK
Bispebjerg Hospital, Copenhagen, Denmark
UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
Southampton General Hospital, Southampton, UK
Prince Philip Hospital, Llanelli, UK
  
Average time to randomisation (last 6 months)
# Hours Hospital
2 1.8 Prince Philip Hospital, Llanelli, UK
2 2.0 Hospital Universitari Vall d'Hebron, Barcelona, Spain
1 2.0 University Hospitals Monkland, Airdrie, UK
7 2.2 Azienda Ospedalieria di Rilievo Nazionale Antonio Cardarelli, Napoli, Italy
23 2.2 Helsinki University Hospital, Helsinki, Finland
6 2.2 St. George's Hospital, London, UK
1 2.3 Tallaght University Hospital, Dublin, Republic of Ireland
2 2.3 Countess of Chester Hospital, Chester, UK
14 2.3 Bispebjerg Hospital, Copenhagen, Denmark
1 2.3 Royal Victoria Hospital, Belfast, UK
1 2.4 Peterborough City Hospital, Peterborough, UK
2 2.5 South West Acute Hospital, County Fermanagh, UK
5 2.5 University Hospital of North Durham, Durham, UK
2 2.5 Royal United Hospital Bath, Bath, UK
3 2.5 Hull Royal Infirmary, Hull, UK
2 2.6 Southend University Hospital, Essex, UK
8 2.7 Royal Infirmary of Edinburgh, Edinburgh, UK
2 2.9 Royal Derby Hospital, Derby, UK
6 2.9 Southampton General Hospital, Southampton, UK
19 2.9 ASST Ovest Milanese, Legnano, Italy
2 2.9 Hôpital Foch, Suresnes, France
16 2.9 The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
2 2.9 University Hospital of North Tees, Stockton on Tees, UK
8 2.9 LTD Pineo Medical Ecosystem, Tbilisi, Georgia
5 3.0 Salford Royal Hospital, Salford, UK
2 3.0 Ninewells Hospital, Dundee, UK
3 3.0 Aintree University Hospital, Liverpool, UK
3 3.0 York Hospital, York, UK
5 3.0 Craigavon Area Hospital, Portadown, UK
11 3.1 Hospital Queen Elizabeth II, Sabah, Malaysia
4 3.1 Queen's Hospital, Romford, UK
13 3.1 Centre Hospitalier Sud Francilien, Paris, France
1 3.1 Northumbria Specialist Emergency Care Hospital, Northumberland, UK
12 3.1 UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
6 3.1 Hospital Tuanku Jaafar, Seremban, Negeri Sembilan, Malaysia
12 3.1 Royal London Hospital, London, UK
5 3.1 New Cross Hospital, Wolverhampton, UK
1 3.1 Kent & Canterbury Hospital, Canterbury, Kent, UK
6 3.1 King's College Hospital, London, UK
2 3.1 Norfolk and Norwich University Hospital, Norwich, UK
3 3.1 Eastbourne General District Hospital, Eastbourne, UK
9 3.1 Charing Cross Hospital, London, UK
7 3.1 Hôpital André Mignot, Le Chesnay, France
2 3.2 Royal Preston Hospital, Preston, UK
4 3.2 Hospital Sultanah Bahiyah, Kedah, Malaysia
9 3.2 LEPL The First University Clinic of Tbilisi State, Tbilisi, Georgia
7 3.2 Hôpital Roger Salengro, Lille, France
7 3.2 The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
6 3.2 James Cook University Hospital, Middlesbrough, UK
4 3.2 Hôpital Lariboisière, Paris, France
2 3.3 Darent Valley Hospital, Dartford, UK
8 3.3 Hospital Seberang Jaya, Pulau Pinang, Malaysia
6 3.3 Royal Stoke University Hospital, Stoke-on-Trent, UK
4 3.3 CHU Rouen, Rouen, France
3 3.3 Hospital Tengku Ampuan Rahimah, Selangor, Malaysia
3 3.3 Hôpital Jean Minjoz, Besançon, France
3 3.3 Cheltenham General Hospital, Cheltenham, UK
2 3.3 CHU Lyon, Lyon, France
6 3.3 Aberdeen Royal Infirmary, Aberdeen, UK
10 3.4 Hospital Queen Elizabeth, Sabah, Malaysia
1 3.4 Antrim Area Hospital, Antrim, UK
6 3.5 Queen's Medical Centre, Nottingham, UK
1 3.5 Arrowe Park Hospital, Wirral, UK
5 3.5 Southmead Hospital, Bristol, UK
2 3.5 Leeds General Infirmary, Leeds, UK
3 3.5 Milton Keynes University Hospital, Milton Keynes, UK
1 3.5 Hospital Umum Sarawak, Sarawak, Malaysia
1 3.6 Hôpital Nord Laennec, Nantes, France
9 3.6 Addenbrooke's Hospital, Cambridge, UK
2 3.6 Leicester Royal Infirmary, Leicester, UK
5 3.6 Lincoln County Hospital, Lincoln, UK
5 3.6 Queen Elizabeth Hospital Birmingham, Birmingham, UK
3 3.6 Luton and Dunstable University Hospital, Luton, UK
4 3.6 Hospital Sultanah Aminah, Johor, Malaysia
1 3.7 Royal Cornwall Hospital, Cornwall, UK
11 3.7 Hôpital Pierre Paul Riquet, Toulouse, France
2 3.8 ASST di Mantova, Mantova, Italy
3 3.9 Ipswich Hospital, Ipswich, UK
1 3.9 Musgrove Park Hospital, Taunton, UK
3 3.9 Yeovil District Hospital, Somerset, UK
3 3.9 Hospital Pengajar UPM, Serdang Selangor, Malaysia
1 3.9 Hospital Universiti Sains Malaysia, Kelantan, Malaysia
5 3.9 Victoria Hospital, Kirkcaldy, UK
1 4.0 Hospital Kuala Lumpur, Kuala Lumpur, Malaysia
1 4.0 Hospital Sultanah Nur Zahirah, Terengganu, Malaysia
1 4.2 Royal Devon and Exeter Hospital, Exeter, UK
3 4.2 Northwick Park Hospital, Harrow, UK
1 4.3 King's Mill Hospital, Sutton in Ashfield, UK
1 4.3 CHU Poitiers, Poitiers, France
1 4.3 University Hospital Coventry, Coventry, UK
1 4.3 Dorset County Hospital, Dorset, UK
1 4.4 Basildon University Hospital, Essex, UK
2 4.5 Royal Hallamshire Hospital, Sheffield, UK
1 4.5 West Suffolk Hospital, Bury St Edmunds, UK
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