TICH-3 trial
Tranexamic acid for IntraCerebral Haemorrhage 3


ISRCTN 97695350
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Room S/D2108, Stroke Trials Unit
School of Medicine, University of Nottingham
Queen's Medical Centre, Derby Road
Nottingham NG7 2UH, United Kingdom
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  • Serious Adverse Events (SAEs) — we have a legal responsibility to collect all safety events occurring within the first 7 days after randomisation (including SARs/SUSARs/fatal SAEs).
  • Safety events include: venous thromboembolism; ischaemic events (arterial thrombosis at any site, ischaemic stroke, transient ischaemic attack, peripheral artery embolism, myocardial infarction, acute coronary syndrome) and seizures.
  • Please remember that fatal SAEs need to be reported, even if after 7 days - unless death occurred after discharge from hospital.
  • Please assess if expected according to RSI.  Expectedness should only be assessed in events that are thought to be possibly/probably/definitely related to the IMP.
  • Investigators have a legal responsibility to report applicable SAEs to the chief investigator without delay, within 24 hours.

Latest recruiting hospitals
Hôpital André Mignot, Le Chesnay, France
Doncaster Royal Infirmary, Doncaster, UK
Odense University Hospital, Odense, Denmark
Hospital Sultanah Bahiyah, Kedah, Malaysia
St. George's Hospital, London, UK
Bispebjerg Hospital, Copenhagen, Denmark
Helsinki University Hospital, Helsinki, Finland
Hospital Seberang Jaya, Pulau Pinang, Malaysia
Presidio Ospedale San Carlo, Milano, Italy
Glan Clwyd Hospital, Denbighshire, UK
Queen's Medical Centre, Nottingham, UK
Hospital Queen Elizabeth, Sabah, Malaysia
ASST Ovest Milanese, Legnano, Italy
Peterborough City Hospital, Peterborough, UK
The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
  
Average time to randomisation (last 6 months)
# Hours Hospital
1 0.8 Hospital UiTM, Selangor, Malaysia
1 1.5 LTD Pineo Medical Ecosystem, Tbilisi, Georgia
1 1.8 Southend University Hospital, Essex, UK
6 2.0 Azienda Ospedalieria di Rilievo Nazionale Antonio Cardarelli, Napoli, Italy
1 2.0 Azienda USL Toscana Nord Ovest, Massa, Italy
4 2.2 Royal Victoria Hospital, Belfast, UK
25 2.3 Bispebjerg Hospital, Copenhagen, Denmark
4 2.3 Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
4 2.4 Aarhus University Hospital, Aarhus, Denmark
13 2.4 Aalborg University Hospital, Gistrup, Denmark
1 2.4 Milton Keynes University Hospital, Milton Keynes, UK
13 2.5 ASST Ovest Milanese, Legnano, Italy
15 2.5 Helsinki University Hospital, Helsinki, Finland
4 2.5 Aintree University Hospital, Liverpool, UK
6 2.6 Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France
1 2.6 Doncaster Royal Infirmary, Doncaster, UK
4 2.6 Royal London Hospital, London, UK
6 2.6 Eastbourne General District Hospital, Eastbourne, UK
9 2.6 CHU Lyon, Lyon, France
11 2.7 The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
13 2.7 Hospital Universitario de A Coruña, A Coruña, Spain
3 2.7 Leeds General Infirmary, Leeds, UK
2 2.8 LEPL The First University Clinic of Tbilisi State, Tbilisi, Georgia
11 2.8 St. George's Hospital, London, UK
2 2.8 Norfolk and Norwich University Hospital, Norwich, UK
4 2.8 Leicester Royal Infirmary, Leicester, UK
6 2.9 Northumbria Specialist Emergency Care Hospital, Northumberland, UK
1 2.9 Royal Infirmary of Edinburgh, Edinburgh, UK
5 2.9 Southmead Hospital, Bristol, UK
1 3.0 Musgrove Park Hospital, Taunton, UK
4 3.0 Whiston Hospital, Merseyside, UK
7 3.0 Hospital Universitari Vall d'Hebron, Barcelona, Spain
2 3.0 Royal Preston Hospital, Preston, UK
2 3.1 Royal Derby Hospital, Derby, UK
9 3.1 Odense University Hospital, Odense, Denmark
10 3.1 Hôpital Nord Laennec, Nantes, France
4 3.1 Lincoln County Hospital, Lincoln, UK
2 3.1 Southampton General Hospital, Southampton, UK
7 3.1 Presidio Ospedale San Carlo, Milano, Italy
3 3.1 Kent & Canterbury Hospital, Canterbury, Kent, UK
4 3.1 Hôpital Foch, Suresnes, France
5 3.2 Hospital Queen Elizabeth II, Sabah, Malaysia
2 3.2 Ninewells Hospital, Dundee, UK
1 3.2 Hôpital André Mignot, Le Chesnay, France
12 3.2 Hospital Universitari de Girona Dr Josep Trueta, Girona, Spain
4 3.2 Charing Cross Hospital, London, UK
4 3.2 James Cook University Hospital, Middlesbrough, UK
18 3.2 The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
4 3.2 Aberdeen Royal Infirmary, Aberdeen, UK
6 3.2 Hospital Sultanah Aminah, Johor, Malaysia
2 3.3 Watford General Hospital, Watford, UK
5 3.3 Royal Stoke University Hospital, Stoke-on-Trent, UK
1 3.3 Mater Misericordiae University Hospital, Dublin, Republic of Ireland
3 3.3 Rigshospitalet, Copenhagen, Denmark
4 3.3 Ipswich Hospital, Ipswich, UK
4 3.3 Addenbrooke's Hospital, Cambridge, UK
5 3.3 Victoria Hospital, Kirkcaldy, UK
20 3.3 Hospital Queen Elizabeth, Sabah, Malaysia
3 3.3 New Cross Hospital, Wolverhampton, UK
4 3.3 Tallaght University Hospital, Dublin, Republic of Ireland
1 3.4 York Hospital, York, UK
16 3.4 UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
2 3.4 King's Mill Hospital, Sutton in Ashfield, UK
6 3.4 Hospital Tengku Ampuan Rahimah, Selangor, Malaysia
4 3.5 Hull Royal Infirmary, Hull, UK
2 3.5 Hospital Tuanku Jaafar, Seremban, Negeri Sembilan, Malaysia
6 3.5 Hôpital Pierre Paul Riquet, Toulouse, France
11 3.5 Hospital Sultanah Bahiyah, Kedah, Malaysia
3 3.6 Hôpital Pellegrin Bordeaux, Bordeaux, France
5 3.6 Centre Hospitalier Sud Francilien, Paris, France
2 3.6 Peterborough City Hospital, Peterborough, UK
3 3.6 Cheltenham General Hospital, Cheltenham, UK
7 3.7 Queen's Medical Centre, Nottingham, UK
6 3.7 King's College Hospital, London, UK
3 3.7 Morriston Hospital, Swansea, UK
4 3.7 Hospital Seberang Jaya, Pulau Pinang, Malaysia
2 3.7 University Hospitals Monkland, Airdrie, UK
1 3.8 Luton and Dunstable University Hospital, Luton, UK
2 3.8 University Hospital Hairmyres, East Kilbride, UK
2 3.8 Hôpital Roger Salengro, Lille, France
3 3.9 Glan Clwyd Hospital, Denbighshire, UK
5 3.9 University Hospital, Cardiff, UK
1 3.9 Antrim Area Hospital, Antrim, UK
3 3.9 Hôpital Jean Minjoz, Besançon, France
1 4.0 Centre Hospitalier Sainte‐Anne, Paris, France
3 4.0 ASST di Mantova, Mantova, Italy
1 4.0 Royal United Hospital Bath, Bath, UK
4 4.0 CHU Rouen, Rouen, France
2 4.1 University Hospital of North Tees, Stockton on Tees, UK
1 4.1 Craigavon Area Hospital, Portadown, UK
1 4.1 Fairfield General Hospital, Bury, UK
4 4.1 West Suffolk Hospital, Bury St Edmunds, UK
2 4.1 Hôpital Lariboisière, Paris, France
1 4.3 Queen Elizabeth Hospital Birmingham, Birmingham, UK
1 4.5 Bradford Royal Infirmary, Bradford, UK
1 4.5 Salford Royal Hospital, Salford, UK
2 4.5 Derriford Hospital, Plymouth, UK
1 4.6 University Hospital of North Durham, Durham, UK
9 6.2 Kantonsspital St.Gallen, St. Gallen, Switzerland
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