TICH-3 trial
Tranexamic acid for IntraCerebral Haemorrhage 3


ISRCTN 97695350
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Room S/D2108, Stroke Trials Unit
School of Medicine, University of Nottingham
Queen's Medical Centre, Derby Road
Nottingham NG7 2UH, United Kingdom
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  • Serious Adverse Events (SAEs) — we have a legal responsibility to collect all safety events occurring within the first 7 days after randomisation (including SARs/SUSARs/fatal SAEs).
  • Safety events include: venous thromboembolism; ischaemic events (arterial thrombosis at any site, ischaemic stroke, transient ischaemic attack, peripheral artery embolism, myocardial infarction, acute coronary syndrome) and seizures.
  • Please remember that fatal SAEs need to be reported, even if after 7 days - unless death occurred after discharge from hospital.
  • Please assess if expected according to RSI.  Expectedness should only be assessed in events that are thought to be possibly/probably/definitely related to the IMP.
  • Investigators have a legal responsibility to report applicable SAEs to the chief investigator without delay, within 24 hours.

Latest recruiting hospitals
University Hospital, Cardiff, UK
Hôpital Roger Salengro, Lille, France
Queen's Medical Centre, Nottingham, UK
Kantonsspital St.Gallen, St. Gallen, Switzerland
Hospital Queen Elizabeth, Sabah, Malaysia
CHU Lyon, Lyon, France
The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
Hospital Tengku Ampuan Rahimah, Selangor, Malaysia
Hospital Universitari Vall d'Hebron, Barcelona, Spain
ASST di Mantova, Mantova, Italy
King's College Hospital, London, UK
Hôpital Jean Minjoz, Besançon, France
Hospital Seberang Jaya, Pulau Pinang, Malaysia
Hôpital Pierre Paul Riquet, Toulouse, France
ASST Ovest Milanese, Legnano, Italy
  
Average time to randomisation (last 6 months)
# Hours Hospital
1 0.8 Uppsala University Hospital, Uppsala, Sweden
2 1.7 LTD Pineo Medical Ecosystem, Tbilisi, Georgia
1 1.8 Southend University Hospital, Essex, UK
3 1.9 Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
5 2.1 Aarhus University Hospital, Aarhus, Denmark
1 2.3 Royal United Hospital Bath, Bath, UK
2 2.3 Hospital Sultanah Bahiyah, Kedah, Malaysia
4 2.3 Royal Victoria Hospital, Belfast, UK
5 2.3 Azienda Ospedalieria di Rilievo Nazionale Antonio Cardarelli, Napoli, Italy
21 2.3 Helsinki University Hospital, Helsinki, Finland
29 2.4 Bispebjerg Hospital, Copenhagen, Denmark
16 2.6 The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
14 2.6 ASST Ovest Milanese, Legnano, Italy
3 2.6 Lincoln County Hospital, Lincoln, UK
5 2.6 Odense University Hospital, Odense, Denmark
6 2.7 Aberdeen Royal Infirmary, Aberdeen, UK
1 2.7 Hospital UiTM, Selangor, Malaysia
7 2.7 Aalborg University Hospital, Aalborg, Denmark
3 2.7 New Cross Hospital, Wolverhampton, UK
13 2.7 CHU Lyon, Lyon, France
9 2.7 St. George's Hospital, London, UK
6 2.7 Eastbourne General District Hospital, Eastbourne, UK
4 2.7 Norfolk and Norwich University Hospital, Norwich, UK
6 2.7 Royal London Hospital, London, UK
14 2.7 Hospital Universitario de A Coruña, A Coruña, Spain
2 2.8 Hôpital André Mignot, Le Chesnay, France
2 2.8 University Hospitals Monkland, Airdrie, UK
1 2.8 Sunderland Royal Hospital, Tyne and Wear, UK
15 2.8 Hospital Universitari Vall d'Hebron, Barcelona, Spain
2 2.9 Mater Misericordiae University Hospital, Dublin, Republic of Ireland
13 2.9 Hospital Universitari de Girona Dr Josep Trueta, Girona, Spain
1 2.9 Kent & Canterbury Hospital, Canterbury, Kent, UK
1 3.0 Yeovil District Hospital, Somerset, UK
4 3.0 Hospital Queen Elizabeth II, Sabah, Malaysia
7 3.0 Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France
6 3.0 Royal Preston Hospital, Preston, UK
1 3.0 Musgrove Park Hospital, Taunton, UK
1 3.1 Milton Keynes University Hospital, Milton Keynes, UK
10 3.1 Presidio Ospedale San Carlo, Milano, Italy
5 3.1 Southmead Hospital, Bristol, UK
5 3.1 University Hospital of North Durham, Durham, UK
2 3.1 Whiston Hospital, Merseyside, UK
6 3.1 Royal Stoke University Hospital, Stoke-on-Trent, UK
9 3.1 Leicester Royal Infirmary, Leicester, UK
5 3.1 Derriford Hospital, Plymouth, UK
9 3.2 LEPL The First University Clinic of Tbilisi State, Tbilisi, Georgia
6 3.2 Cheltenham General Hospital, Cheltenham, UK
6 3.2 James Cook University Hospital, Middlesbrough, UK
6 3.2 Hôpital Foch, Suresnes, France
2 3.3 Hospital Kuala Lumpur, Kuala Lumpur, Malaysia
1 3.3 Hospital Tuanku Jaafar, Seremban, Negeri Sembilan, Malaysia
2 3.3 Watford General Hospital, Watford, UK
5 3.3 Hospital Sultanah Aminah, Johor, Malaysia
3 3.3 Centre Hospitalier Sainte‐Anne, Paris, France
15 3.3 Hospital Queen Elizabeth, Sabah, Malaysia
18 3.3 The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
7 3.3 Hôpital Nord Laennec, Nantes, France
4 3.3 Tallaght University Hospital, Dublin, Republic of Ireland
17 3.4 UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
6 3.4 Hôpital Pierre Paul Riquet, Toulouse, France
5 3.4 Queen's Medical Centre, Nottingham, UK
3 3.4 Hôpital Pellegrin Bordeaux, Bordeaux, France
3 3.4 Hôpital Jean Minjoz, Besançon, France
2 3.4 Azienda USL Toscana Nord Ovest, Massa, Italy
3 3.4 Hospital Seberang Jaya, Pulau Pinang, Malaysia
1 3.4 CHU Rouen, Rouen, France
8 3.4 Charing Cross Hospital, London, UK
1 3.4 Aintree University Hospital, Liverpool, UK
7 3.4 King's College Hospital, London, UK
5 3.5 Addenbrooke's Hospital, Cambridge, UK
4 3.5 Craigavon Area Hospital, Portadown, UK
2 3.5 Salford Royal Hospital, Salford, UK
3 3.5 Ninewells Hospital, Dundee, UK
2 3.6 Hull Royal Infirmary, Hull, UK
7 3.6 Kantonsspital St.Gallen, St. Gallen, Switzerland
8 3.6 Ipswich Hospital, Ipswich, UK
3 3.6 York Hospital, York, UK
2 3.6 Hôpital Lariboisière, Paris, France
3 3.6 University Hospital of North Tees, Stockton on Tees, UK
10 3.7 Centre Hospitalier Sud Francilien, Paris, France
4 3.7 Victoria Hospital, Kirkcaldy, UK
1 3.8 Luton and Dunstable University Hospital, Luton, UK
4 3.8 Morriston Hospital, Swansea, UK
2 3.8 Royal Bournemouth Hospital, Bournemouth, UK
2 3.8 Royal Infirmary of Edinburgh, Edinburgh, UK
1 3.8 Countess of Chester Hospital, Chester, UK
1 3.9 Rigshospitalet, Copenhagen, Denmark
2 3.9 ASST di Mantova, Mantova, Italy
2 4.0 West Suffolk Hospital, Bury St Edmunds, UK
3 4.0 Hôpital Roger Salengro, Lille, France
3 4.0 Royal Derby Hospital, Derby, UK
2 4.2 Glan Clwyd Hospital, Denbighshire, UK
2 4.2 Queen Elizabeth Hospital Birmingham, Birmingham, UK
6 4.2 Hospital Tengku Ampuan Rahimah, Selangor, Malaysia
3 4.2 University Hospital, Cardiff, UK
1 4.3 University Hospital Hairmyres, East Kilbride, UK
1 4.4 CHU Poitiers, Poitiers, France
1 4.6 Peterborough City Hospital, Peterborough, UK
Documents