TICH-3 trial
Tranexamic acid for IntraCerebral Haemorrhage 3


ISRCTN 97695350
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Room S/D2108, Stroke Trials Unit
School of Medicine, University of Nottingham
Queen's Medical Centre, Derby Road
Nottingham NG7 2UH, United Kingdom
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  • Serious Adverse Events (SAEs) — we have a legal responsibility to collect all safety events occurring within the first 7 days after randomisation (including SARs/SUSARs/fatal SAEs).
  • Safety events include: venous thromboembolism; ischaemic events (arterial thrombosis at any site, ischaemic stroke, transient ischaemic attack, peripheral artery embolism, myocardial infarction, acute coronary syndrome) and seizures.
  • Please remember that fatal SAEs need to be reported, even if after 7 days - unless death occurred after discharge from hospital.
  • Please assess if expected according to SmPC.  Expectedness should only be assessed in events that are thought to be possibly/probably/definitely related to the IMP.
  • Investigators have a legal responsibility to report applicable SAEs to the chief investigator without delay, within 24 hours.

Latest recruiting hospitals
Bispebjerg Hospital, Copenhagen, Denmark
St. George's Hospital, London, UK
Hospital Universitari Vall d'Hebron, Barcelona, Spain
King's Mill Hospital, Sutton in Ashfield, UK
Eastbourne General District Hospital, Eastbourne, UK
James Cook University Hospital, Middlesbrough, UK
Hospital Umum Sarawak, Sarawak, Malaysia
Charing Cross Hospital, London, UK
Azienda Ospedalieria di Rilievo Nazionale Antonio Cardarelli, Napoli, Italy
Hospital Queen Elizabeth II, Sabah, Malaysia
Southampton General Hospital, Southampton, UK
Southmead Hospital, Bristol, UK
Norfolk and Norwich University Hospital, Norwich, UK
Hôpital André Mignot, Le Chesnay, France
Tallaght University Hospital, Dublin, Republic of Ireland
  
Average time to randomisation (last 6 months)
# Hours Hospital
2 1.8 Prince Philip Hospital, Llanelli, UK
1 2.0 Hôpital Foch, Suresnes, France
1 2.0 University Hospitals Monkland, Airdrie, UK
20 2.2 Helsinki University Hospital, Helsinki, Finland
2 2.3 Countess of Chester Hospital, Chester, UK
16 2.3 Bispebjerg Hospital, Copenhagen, Denmark
9 2.3 Azienda Ospedalieria di Rilievo Nazionale Antonio Cardarelli, Napoli, Italy
1 2.3 Royal Victoria Hospital, Belfast, UK
6 2.4 St. George's Hospital, London, UK
1 2.4 Peterborough City Hospital, Peterborough, UK
2 2.5 South West Acute Hospital, County Fermanagh, UK
5 2.5 University Hospital of North Durham, Durham, UK
2 2.5 Royal United Hospital Bath, Bath, UK
3 2.5 Hull Royal Infirmary, Hull, UK
2 2.6 Southend University Hospital, Essex, UK
4 2.7 Tallaght University Hospital, Dublin, Republic of Ireland
4 2.7 Craigavon Area Hospital, Portadown, UK
16 2.7 ASST Ovest Milanese, Legnano, Italy
7 2.8 Royal Infirmary of Edinburgh, Edinburgh, UK
2 2.8 Hôpital Jean Minjoz, Besançon, France
9 2.8 Hospital Queen Elizabeth II, Sabah, Malaysia
9 2.8 LTD Pineo Medical Ecosystem, Tbilisi, Georgia
2 2.9 Royal Derby Hospital, Derby, UK
11 2.9 Centre Hospitalier Sud Francilien, Paris, France
6 2.9 Salford Royal Hospital, Salford, UK
4 2.9 Hospital Universitari Vall d'Hebron, Barcelona, Spain
16 3.0 The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
2 3.0 Ninewells Hospital, Dundee, UK
3 3.0 Aintree University Hospital, Liverpool, UK
3 3.0 York Hospital, York, UK
12 3.0 UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
4 3.1 Queen's Hospital, Romford, UK
1 3.1 Northumbria Specialist Emergency Care Hospital, Northumberland, UK
6 3.1 Hospital Tuanku Jaafar, Seremban, Negeri Sembilan, Malaysia
12 3.1 Royal London Hospital, London, UK
5 3.1 New Cross Hospital, Wolverhampton, UK
1 3.1 Kent & Canterbury Hospital, Canterbury, Kent, UK
3 3.1 University Hospital of North Tees, Stockton on Tees, UK
2 3.2 Royal Preston Hospital, Preston, UK
6 3.2 Southampton General Hospital, Southampton, UK
5 3.2 Aberdeen Royal Infirmary, Aberdeen, UK
8 3.2 Hôpital André Mignot, Le Chesnay, France
7 3.2 Hôpital Roger Salengro, Lille, France
7 3.2 The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
4 3.2 Hôpital Lariboisière, Paris, France
2 3.3 Darent Valley Hospital, Dartford, UK
9 3.3 Charing Cross Hospital, London, UK
8 3.3 Hospital Seberang Jaya, Pulau Pinang, Malaysia
6 3.3 Royal Stoke University Hospital, Stoke-on-Trent, UK
4 3.3 CHU Rouen, Rouen, France
3 3.3 Norfolk and Norwich University Hospital, Norwich, UK
3 3.3 Hospital Tengku Ampuan Rahimah, Selangor, Malaysia
5 3.3 King's College Hospital, London, UK
3 3.3 Hospital Sultanah Bahiyah, Kedah, Malaysia
3 3.3 Cheltenham General Hospital, Cheltenham, UK
8 3.3 LEPL The First University Clinic of Tbilisi State, Tbilisi, Georgia
2 3.3 CHU Lyon, Lyon, France
2 3.4 Hospital Umum Sarawak, Sarawak, Malaysia
9 3.4 Hospital Queen Elizabeth, Sabah, Malaysia
1 3.4 Antrim Area Hospital, Antrim, UK
5 3.5 Eastbourne General District Hospital, Eastbourne, UK
8 3.5 James Cook University Hospital, Middlesbrough, UK
1 3.5 Arrowe Park Hospital, Wirral, UK
5 3.5 Queen's Medical Centre, Nottingham, UK
2 3.5 Leeds General Infirmary, Leeds, UK
8 3.5 Addenbrooke's Hospital, Cambridge, UK
3 3.5 Milton Keynes University Hospital, Milton Keynes, UK
3 3.5 ASST di Mantova, Mantova, Italy
5 3.6 Southmead Hospital, Bristol, UK
1 3.6 Hôpital Nord Laennec, Nantes, France
1 3.6 Doncaster Royal Infirmary, Doncaster, UK
2 3.6 Leicester Royal Infirmary, Leicester, UK
5 3.6 Lincoln County Hospital, Lincoln, UK
5 3.6 Queen Elizabeth Hospital Birmingham, Birmingham, UK
3 3.6 Hospital Sultanah Aminah, Johor, Malaysia
4 3.7 Ipswich Hospital, Ipswich, UK
1 3.7 Royal Cornwall Hospital, Cornwall, UK
10 3.7 Hôpital Pierre Paul Riquet, Toulouse, France
2 3.8 Luton and Dunstable University Hospital, Luton, UK
4 3.8 Victoria Hospital, Kirkcaldy, UK
1 3.9 Musgrove Park Hospital, Taunton, UK
3 3.9 Yeovil District Hospital, Somerset, UK
3 3.9 Hospital Pengajar UPM, Serdang Selangor, Malaysia
1 3.9 Hospital Universiti Sains Malaysia, Kelantan, Malaysia
1 4.0 Hospital Kuala Lumpur, Kuala Lumpur, Malaysia
1 4.0 Hospital Sultanah Nur Zahirah, Terengganu, Malaysia
2 4.1 King's Mill Hospital, Sutton in Ashfield, UK
1 4.2 Royal Devon and Exeter Hospital, Exeter, UK
3 4.2 Northwick Park Hospital, Harrow, UK
1 4.3 CHU Poitiers, Poitiers, France
1 4.3 University Hospital Coventry, Coventry, UK
1 4.3 Dorset County Hospital, Dorset, UK
1 4.4 Basildon University Hospital, Essex, UK
2 4.5 Royal Hallamshire Hospital, Sheffield, UK
1 4.5 West Suffolk Hospital, Bury St Edmunds, UK
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