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TICH-3 trial

Tranexamic acid for IntraCerebral Haemorrhage 3

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SA-04-22

SA-04-22

  1. This substantial amendment comprises changes to the protocol. Primarily to include patients into the TICH-3 trial that have had an Intracranial haemorrhage (ICH) while on Direct Oral Anticoagulant (DOAC). This was supported by the findings from the TICH- NOAC trial undertaken by Prof Lyrer et al in Switzerland. Enabling this protocol amendment will allow prompt recruitment of patients to the trial that are on DOACs experiencing ICH.
  2. Other formatting changes and small clarifications have been made, full details can be viewed within the locked amendment tool document.



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