TICH-3 trial
Tranexamic acid for IntraCerebral Haemorrhage 3


ISRCTN 97695350
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Room S/D2108, Stroke Trials Unit
School of Medicine, University of Nottingham
Queen's Medical Centre, Derby Road
Nottingham NG7 2UH, United Kingdom
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  • Serious Adverse Events (SAEs) — we have a legal responsibility to collect all safety events occurring within the first 7 days after randomisation (including SARs/SUSARs/fatal SAEs).
  • Safety events include: venous thromboembolism; ischaemic events (arterial thrombosis at any site, ischaemic stroke, transient ischaemic attack, peripheral artery embolism, myocardial infarction, acute coronary syndrome) and seizures.
  • Please remember that fatal SAEs need to be reported, even if after 7 days - unless death occurred after discharge from hospital.
  • Please assess if expected according to SmPC.  Expectedness should only be assessed in events that are thought to be possibly/probably/definitely related to the IMP.
  • Investigators have a legal responsibility to report applicable SAEs to the chief investigator without delay, within 24 hours.

Latest recruiting hospitals
Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France
Royal London Hospital, London, UK
Craigavon Area Hospital, Portadown, UK
Hôpital Foch, Suresnes, France
University Hospital of North Durham, Durham, UK
Hospital Queen Elizabeth, Sabah, Malaysia
Morriston Hospital, Swansea, UK
Doncaster Royal Infirmary, Doncaster, UK
Royal Alexandra Hospital, Paisley, UK
Helsinki University Hospital, Helsinki, Finland
Aberdeen Royal Infirmary, Aberdeen, UK
LEPL The First University Clinic of Tbilisi State, Tbilisi, Georgia
Aintree University Hospital, Liverpool, UK
Kantonsspital St.Gallen, St. Gallen, Switzerland
James Cook University Hospital, Middlesbrough, UK
  
Average time to randomisation (last 6 months)
# Hours Hospital
1 1.3 York Hospital, York, UK
1 1.6 Milton Keynes University Hospital, Milton Keynes, UK
10 1.8 LTD Pineo Medical Ecosystem, Tbilisi, Georgia
1 2.3 King's College Hospital, London, UK
6 2.3 Royal Infirmary of Edinburgh, Edinburgh, UK
9 2.3 Azienda Ospedalieria di Rilievo Nazionale Antonio Cardarelli, Napoli, Italy
4 2.4 Aarhus University Hospital, Aarhus, Denmark
3 2.4 Queen's Medical Centre, Nottingham, UK
26 2.5 Helsinki University Hospital, Helsinki, Finland
3 2.6 King's Mill Hospital, Sutton in Ashfield, UK
23 2.6 Bispebjerg Hospital, Copenhagen, Denmark
1 2.6 Hôpital Jean Minjoz, Besançon, France
1 2.6 Sunderland Royal Hospital, Tyne and Wear, UK
1 2.6 Royal United Hospital Bath, Bath, UK
4 2.6 Eastbourne General District Hospital, Eastbourne, UK
2 2.7 Ipswich Hospital, Ipswich, UK
9 2.7 St. George's Hospital, London, UK
4 2.7 Hôpital André Mignot, Le Chesnay, France
5 2.7 Derriford Hospital, Plymouth, UK
4 2.7 Ninewells Hospital, Dundee, UK
1 2.8 Fairfield General Hospital, Bury, UK
9 2.8 Hospital Universitari Vall d'Hebron, Barcelona, Spain
16 2.8 ASST Ovest Milanese, Legnano, Italy
2 2.8 Royal Derby Hospital, Derby, UK
1 2.8 Queen's Hospital, Romford, UK
5 2.8 Norfolk and Norwich University Hospital, Norwich, UK
9 2.8 Aintree University Hospital, Liverpool, UK
1 2.8 Leighton Hospital, Crewe, UK
3 2.8 CHU Rouen, Rouen, France
11 2.8 CHU Lyon, Lyon, France
3 2.8 Southampton General Hospital, Southampton, UK
10 2.9 Hospital Queen Elizabeth, Sabah, Malaysia
13 2.9 LEPL The First University Clinic of Tbilisi State, Tbilisi, Georgia
5 3.0 Royal Victoria Hospital, Belfast, UK
4 3.0 Morriston Hospital, Swansea, UK
4 3.0 Leicester Royal Infirmary, Leicester, UK
6 3.0 Hospital Universitario de A Coruña, A Coruña, Spain
5 3.1 Lincoln County Hospital, Lincoln, UK
2 3.1 Salford Royal Hospital, Salford, UK
4 3.1 Hospital Tuanku Jaafar, Seremban, Negeri Sembilan, Malaysia
1 3.1 Uppsala University Hospital, Uppsala, Sweden
7 3.1 UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
6 3.1 Hôpital Lariboisière, Paris, France
5 3.1 Doncaster Royal Infirmary, Doncaster, UK
3 3.2 Hôpital Foch, Suresnes, France
16 3.2 Kantonsspital St.Gallen, St. Gallen, Switzerland
4 3.2 Victoria Hospital, Kirkcaldy, UK
2 3.2 Arrowe Park Hospital, Wirral, UK
5 3.2 Charing Cross Hospital, London, UK
9 3.2 Royal Hallamshire Hospital, Sheffield, UK
9 3.3 New Cross Hospital, Wolverhampton, UK
4 3.3 Craigavon Area Hospital, Portadown, UK
5 3.3 ASST di Mantova, Mantova, Italy
18 3.3 The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
5 3.4 Hull Royal Infirmary, Hull, UK
16 3.4 Centre Hospitalier Sud Francilien, Paris, France
9 3.4 The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
4 3.4 Royal Preston Hospital, Preston, UK
6 3.4 Hospital Tengku Ampuan Rahimah, Selangor, Malaysia
8 3.4 Hôpital Pierre Paul Riquet, Toulouse, France
2 3.4 CHU Poitiers, Poitiers, France
2 3.4 Hospital Umum Sarawak, Sarawak, Malaysia
8 3.4 Tallaght University Hospital, Dublin, Republic of Ireland
6 3.4 University Hospital of North Durham, Durham, UK
10 3.4 Royal London Hospital, London, UK
8 3.4 Hospital Sultanah Aminah, Johor, Malaysia
5 3.5 Hospital Queen Elizabeth II, Sabah, Malaysia
4 3.5 Cheltenham General Hospital, Cheltenham, UK
1 3.5 Southend University Hospital, Essex, UK
5 3.5 Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France
4 3.5 Southmead Hospital, Bristol, UK
6 3.5 James Cook University Hospital, Middlesbrough, UK
4 3.6 Hôpital Roger Salengro, Lille, France
5 3.6 Hôpital Pellegrin Bordeaux, Bordeaux, France
5 3.6 Hospital UiTM, Selangor, Malaysia
3 3.6 Hôpital Nord Laennec, Nantes, France
2 3.7 University Hospital Coventry, Coventry, UK
7 3.7 Royal Stoke University Hospital, Stoke-on-Trent, UK
1 3.7 Hospital Sultanah Bahiyah, Kedah, Malaysia
2 3.7 Antrim Area Hospital, Antrim, UK
2 3.8 Leeds General Infirmary, Leeds, UK
1 3.8 Cumberland Infirmary, Carlisle, UK
2 3.8 Addenbrooke's Hospital, Cambridge, UK
2 3.8 Dorset County Hospital, Dorset, UK
1 3.8 Watford General Hospital, Watford, UK
8 3.9 Aberdeen Royal Infirmary, Aberdeen, UK
6 3.9 Hospital Seberang Jaya, Pulau Pinang, Malaysia
2 3.9 Royal Cornwall Hospital, Cornwall, UK
2 3.9 Hospital Pengajar UPM, Serdang Selangor, Malaysia
1 3.9 Queen Elizabeth Hospital Birmingham, Birmingham, UK
3 4.0 Luton and Dunstable University Hospital, Luton, UK
1 4.1 Royal Alexandra Hospital, Paisley, UK
2 4.1 University Hospital of North Tees, Stockton on Tees, UK
2 4.2 Royal Devon and Exeter Hospital, Exeter, UK
1 4.4 Kent & Canterbury Hospital, Canterbury, Kent, UK
1 4.5 Centre Hospitalier Sainte‐Anne, Paris, France
1 4.5 West Suffolk Hospital, Bury St Edmunds, UK
2 4.6 Princess Royal University Hospital, Orpington, UK
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