TICH-3 trial
Tranexamic acid for IntraCerebral Haemorrhage 3


ISRCTN 97695350
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Room S/D2108, Stroke Trials Unit
School of Medicine, University of Nottingham
Queen's Medical Centre, Derby Road
Nottingham NG7 2UH, United Kingdom
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  • Serious Adverse Events (SAEs) — we have a legal responsibility to collect all safety events occurring within the first 7 days after randomisation (including SARs/SUSARs/fatal SAEs).
  • Safety events include: venous thromboembolism; ischaemic events (arterial thrombosis at any site, ischaemic stroke, transient ischaemic attack, peripheral artery embolism, myocardial infarction, acute coronary syndrome) and seizures.
  • Please remember that fatal SAEs need to be reported, even if after 7 days - unless death occurred after discharge from hospital.
  • Please assess if expected according to RSI.  Expectedness should only be assessed in events that are thought to be possibly/probably/definitely related to the IMP.
  • Investigators have a legal responsibility to report applicable SAEs to the chief investigator without delay, within 24 hours.

Latest recruiting hospitals
Royal Stoke University Hospital, Stoke-on-Trent, UK
Glan Clwyd Hospital, Denbighshire, UK
Addenbrooke's Hospital, Cambridge, UK
Hospital Universitario de A Coruña, A Coruña, Spain
Hull Royal Infirmary, Hull, UK
St. George's Hospital, London, UK
The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
Tallaght University Hospital, Dublin, Republic of Ireland
Whiston Hospital, Merseyside, UK
Hospital Tengku Ampuan Rahimah, Selangor, Malaysia
Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France
Helsinki University Hospital, Helsinki, Finland
Presidio Ospedale San Carlo, Milano, Italy
Eastbourne General District Hospital, Eastbourne, UK
The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
  
Average time to randomisation (last 6 months)
# Hours Hospital
1 0.8 Uppsala University Hospital, Uppsala, Sweden
2 1.9 Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
20 2.1 Helsinki University Hospital, Helsinki, Finland
4 2.2 Aarhus University Hospital, Aarhus, Denmark
29 2.2 Bispebjerg Hospital, Copenhagen, Denmark
4 2.2 Azienda Ospedalieria di Rilievo Nazionale Antonio Cardarelli, Napoli, Italy
1 2.2 Kent & Canterbury Hospital, Canterbury, Kent, UK
1 2.3 University Hospitals Monkland, Airdrie, UK
1 2.3 Royal United Hospital Bath, Bath, UK
3 2.3 Odense University Hospital, Odense, Denmark
1 2.3 Arrowe Park Hospital, Wirral, UK
2 2.5 LTD Pineo Medical Ecosystem, Tbilisi, Georgia
14 2.5 Hospital Universitari Vall d'Hebron, Barcelona, Spain
5 2.5 Aberdeen Royal Infirmary, Aberdeen, UK
1 2.5 Mater Misericordiae University Hospital, Dublin, Republic of Ireland
11 2.5 ASST Ovest Milanese, Legnano, Italy
8 2.6 St. George's Hospital, London, UK
14 2.6 The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
1 2.7 Hospital UiTM, Selangor, Malaysia
12 2.7 Hospital Universitari de Girona Dr Josep Trueta, Girona, Spain
16 2.8 Hospital Universitario de A Coruña, A Coruña, Spain
3 2.8 Royal Victoria Hospital, Belfast, UK
10 2.8 CHU Lyon, Lyon, France
2 2.8 Yeovil District Hospital, Somerset, UK
1 2.8 Sunderland Royal Hospital, Tyne and Wear, UK
7 2.8 Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France
7 2.9 Derriford Hospital, Plymouth, UK
6 3.0 Hôpital Foch, Suresnes, France
5 3.0 Hôpital André Mignot, Le Chesnay, France
5 3.1 Cheltenham General Hospital, Cheltenham, UK
1 3.1 Milton Keynes University Hospital, Milton Keynes, UK
5 3.1 Eastbourne General District Hospital, Eastbourne, UK
2 3.1 Whiston Hospital, Merseyside, UK
5 3.1 Royal Stoke University Hospital, Stoke-on-Trent, UK
8 3.1 Norfolk and Norwich University Hospital, Norwich, UK
3 3.1 King's College Hospital, London, UK
9 3.1 LEPL The First University Clinic of Tbilisi State, Tbilisi, Georgia
7 3.2 Leicester Royal Infirmary, Leicester, UK
7 3.2 University Hospital of North Durham, Durham, UK
2 3.2 Hospital Seberang Jaya, Pulau Pinang, Malaysia
6 3.2 James Cook University Hospital, Middlesbrough, UK
8 3.2 Hospital Queen Elizabeth, Sabah, Malaysia
6 3.2 Royal London Hospital, London, UK
7 3.2 Hôpital Pierre Paul Riquet, Toulouse, France
3 3.2 Hospital Queen Elizabeth II, Sabah, Malaysia
5 3.2 Royal Preston Hospital, Preston, UK
1 3.3 Hôpital Lariboisière, Paris, France
2 3.3 Hospital Kuala Lumpur, Kuala Lumpur, Malaysia
21 3.3 The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
8 3.3 Presidio Ospedale San Carlo, Milano, Italy
3 3.3 CHU Rouen, Rouen, France
2 3.3 Luton and Dunstable University Hospital, Luton, UK
4 3.3 Craigavon Area Hospital, Portadown, UK
4 3.3 New Cross Hospital, Wolverhampton, UK
8 3.3 Charing Cross Hospital, London, UK
7 3.3 Hôpital Nord Laennec, Nantes, France
8 3.4 UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
3 3.4 Southmead Hospital, Bristol, UK
2 3.4 West Suffolk Hospital, Bury St Edmunds, UK
2 3.4 Azienda USL Toscana Nord Ovest, Massa, Italy
4 3.4 Centre Hospitalier Sainte‐Anne, Paris, France
4 3.5 Hôpital Pellegrin Bordeaux, Bordeaux, France
2 3.5 Salford Royal Hospital, Salford, UK
1 3.5 Watford General Hospital, Watford, UK
4 3.5 York Hospital, York, UK
3 3.5 Aintree University Hospital, Liverpool, UK
3 3.5 Southampton General Hospital, Southampton, UK
2 3.6 Hull Royal Infirmary, Hull, UK
2 3.6 Victoria Hospital, Kirkcaldy, UK
3 3.6 Hôpital Jean Minjoz, Besançon, France
5 3.6 University Hospital of North Tees, Stockton on Tees, UK
2 3.6 Hôpital Roger Salengro, Lille, France
6 3.6 Addenbrooke's Hospital, Cambridge, UK
8 3.6 Centre Hospitalier Sud Francilien, Paris, France
7 3.6 Kantonsspital St.Gallen, St. Gallen, Switzerland
3 3.7 Ninewells Hospital, Dundee, UK
4 3.8 Morriston Hospital, Swansea, UK
5 3.8 Queen's Medical Centre, Nottingham, UK
2 3.8 Royal Infirmary of Edinburgh, Edinburgh, UK
7 3.8 Ipswich Hospital, Ipswich, UK
1 3.8 Countess of Chester Hospital, Chester, UK
3 3.9 Royal Bournemouth Hospital, Bournemouth, UK
3 3.9 Royal Derby Hospital, Derby, UK
2 3.9 Antrim Area Hospital, Antrim, UK
1 4.0 University Hospital Coventry, Coventry, UK
1 4.1 Royal Cornwall Hospital, Cornwall, UK
4 4.1 Hospital Tengku Ampuan Rahimah, Selangor, Malaysia
1 4.2 Hospital Sultanah Aminah, Johor, Malaysia
2 4.2 Queen Elizabeth Hospital Birmingham, Birmingham, UK
1 4.5 Glan Clwyd Hospital, Denbighshire, UK
1 4.5 Tallaght University Hospital, Dublin, Republic of Ireland
1 4.5 Northwick Park Hospital, Harrow, UK
1 4.6 Peterborough City Hospital, Peterborough, UK
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