TICH-3 trial
Tranexamic acid for IntraCerebral Haemorrhage 3


ISRCTN 97695350
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Room S/D2108, Stroke Trials Unit
School of Medicine, University of Nottingham
Queen's Medical Centre, Derby Road
Nottingham NG7 2UH, United Kingdom
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  • Serious Adverse Events (SAEs) — we have a legal responsibility to collect all safety events occurring within the first 7 days after randomisation (including SARs/SUSARs/fatal SAEs).
  • Safety events include: venous thromboembolism; ischaemic events (arterial thrombosis at any site, ischaemic stroke, transient ischaemic attack, peripheral artery embolism, myocardial infarction, acute coronary syndrome) and seizures.
  • Please remember that fatal SAEs need to be reported, even if after 7 days - unless death occurred after discharge from hospital.
  • Please assess if expected according to RSI.  Expectedness should only be assessed in events that are thought to be possibly/probably/definitely related to the IMP.
  • Investigators have a legal responsibility to report applicable SAEs to the chief investigator without delay, within 24 hours.

Latest recruiting hospitals
Hospital Sultanah Bahiyah, Kedah, Malaysia
University Hospital Hairmyres, East Kilbride, UK
Royal Stoke University Hospital, Stoke-on-Trent, UK
UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
Leicester Royal Infirmary, Leicester, UK
The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
Hospital Universitari Vall d'Hebron, Barcelona, Spain
Royal United Hospital Bath, Bath, UK
Hospital Queen Elizabeth, Sabah, Malaysia
Aalborg University Hospital, Gistrup, Denmark
Centre Hospitalier Sud Francilien, Paris, France
Leeds General Infirmary, Leeds, UK
Kantonsspital St.Gallen, St. Gallen, Switzerland
Hospital UiTM, Selangor, Malaysia
Hospital Universitari de Girona Dr Josep Trueta, Girona, Spain
  
Average time to randomisation (last 6 months)
# Hours Hospital
1 0.8 Uppsala University Hospital, Uppsala, Sweden
1 0.8 Hospital UiTM, Selangor, Malaysia
2 1.7 LTD Pineo Medical Ecosystem, Tbilisi, Georgia
1 1.8 Southend University Hospital, Essex, UK
1 2.0 Azienda USL Toscana Nord Ovest, Massa, Italy
4 2.2 Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
5 2.2 Azienda Ospedalieria di Rilievo Nazionale Antonio Cardarelli, Napoli, Italy
4 2.3 Royal London Hospital, London, UK
5 2.4 Royal Victoria Hospital, Belfast, UK
19 2.4 Helsinki University Hospital, Helsinki, Finland
1 2.4 Milton Keynes University Hospital, Milton Keynes, UK
6 2.4 Aarhus University Hospital, Aarhus, Denmark
12 2.4 Aalborg University Hospital, Gistrup, Denmark
1 2.5 Ninewells Hospital, Dundee, UK
3 2.5 Norfolk and Norwich University Hospital, Norwich, UK
5 2.5 Eastbourne General District Hospital, Eastbourne, UK
10 2.6 The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
15 2.6 Hospital Universitario de A Coruña, A Coruña, Spain
3 2.6 Lincoln County Hospital, Lincoln, UK
12 2.7 ASST Ovest Milanese, Legnano, Italy
15 2.7 CHU Lyon, Lyon, France
2 2.8 Kent & Canterbury Hospital, Canterbury, Kent, UK
2 2.8 Hôpital André Mignot, Le Chesnay, France
3 2.8 Hospital Queen Elizabeth II, Sabah, Malaysia
8 2.8 Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France
5 2.8 Royal Preston Hospital, Preston, UK
3 2.8 New Cross Hospital, Wolverhampton, UK
14 2.8 Hospital Universitari Vall d'Hebron, Barcelona, Spain
2 2.8 University Hospitals Monkland, Airdrie, UK
1 2.8 Sunderland Royal Hospital, Tyne and Wear, UK
20 2.8 Bispebjerg Hospital, Copenhagen, Denmark
5 2.9 Leicester Royal Infirmary, Leicester, UK
2 2.9 Leeds General Infirmary, Leeds, UK
16 2.9 Hospital Universitari de Girona Dr Josep Trueta, Girona, Spain
1 3.0 Musgrove Park Hospital, Taunton, UK
7 3.1 St. George's Hospital, London, UK
6 3.1 Hôpital Foch, Suresnes, France
10 3.1 Hôpital Nord Laennec, Nantes, France
7 3.1 Aberdeen Royal Infirmary, Aberdeen, UK
5 3.1 Southmead Hospital, Bristol, UK
7 3.1 Odense University Hospital, Odense, Denmark
6 3.1 James Cook University Hospital, Middlesbrough, UK
5 3.2 Cheltenham General Hospital, Cheltenham, UK
6 3.2 Hospital Sultanah Bahiyah, Kedah, Malaysia
8 3.2 LEPL The First University Clinic of Tbilisi State, Tbilisi, Georgia
3 3.2 Whiston Hospital, Merseyside, UK
9 3.2 Presidio Ospedale San Carlo, Milano, Italy
2 3.3 Watford General Hospital, Watford, UK
5 3.3 Hospital Sultanah Aminah, Johor, Malaysia
2 3.3 Royal Infirmary of Edinburgh, Edinburgh, UK
4 3.3 Northumbria Specialist Emergency Care Hospital, Northumberland, UK
5 3.3 Royal Stoke University Hospital, Stoke-on-Trent, UK
18 3.3 Hospital Queen Elizabeth, Sabah, Malaysia
1 3.3 Mater Misericordiae University Hospital, Dublin, Republic of Ireland
3 3.3 Rigshospitalet, Copenhagen, Denmark
17 3.3 The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
3 3.3 Hull Royal Infirmary, Hull, UK
4 3.3 Tallaght University Hospital, Dublin, Republic of Ireland
8 3.3 Hôpital Pierre Paul Riquet, Toulouse, France
19 3.4 UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
2 3.4 Centre Hospitalier Sainte‐Anne, Paris, France
3 3.4 Hôpital Jean Minjoz, Besançon, France
2 3.4 King's Mill Hospital, Sutton in Ashfield, UK
1 3.4 Aintree University Hospital, Liverpool, UK
7 3.4 King's College Hospital, London, UK
3 3.4 Addenbrooke's Hospital, Cambridge, UK
7 3.5 Ipswich Hospital, Ipswich, UK
2 3.5 Hospital Tuanku Jaafar, Seremban, Negeri Sembilan, Malaysia
2 3.5 University Hospital of North Durham, Durham, UK
1 3.6 Southampton General Hospital, Southampton, UK
3 3.6 Hôpital Pellegrin Bordeaux, Bordeaux, France
6 3.6 Hospital Tengku Ampuan Rahimah, Selangor, Malaysia
5 3.6 Charing Cross Hospital, London, UK
2 3.7 York Hospital, York, UK
5 3.7 Victoria Hospital, Kirkcaldy, UK
11 3.7 Centre Hospitalier Sud Francilien, Paris, France
7 3.7 Queen's Medical Centre, Nottingham, UK
1 3.8 Luton and Dunstable University Hospital, Luton, UK
2 3.8 University Hospital Hairmyres, East Kilbride, UK
4 3.8 University Hospital, Cardiff, UK
3 3.8 Hôpital Lariboisière, Paris, France
2 3.8 Derriford Hospital, Plymouth, UK
2 3.8 Hôpital Roger Salengro, Lille, France
2 3.9 Royal Derby Hospital, Derby, UK
1 3.9 Antrim Area Hospital, Antrim, UK
3 4.0 University Hospital of North Tees, Stockton on Tees, UK
3 4.0 Morriston Hospital, Swansea, UK
3 4.0 ASST di Mantova, Mantova, Italy
3 4.0 West Suffolk Hospital, Bury St Edmunds, UK
1 4.0 Royal United Hospital Bath, Bath, UK
1 4.1 Craigavon Area Hospital, Portadown, UK
2 4.2 Glan Clwyd Hospital, Denbighshire, UK
3 4.2 Hospital Seberang Jaya, Pulau Pinang, Malaysia
1 4.3 Queen Elizabeth Hospital Birmingham, Birmingham, UK
2 4.4 CHU Rouen, Rouen, France
1 4.5 Bradford Royal Infirmary, Bradford, UK
2 4.5 Salford Royal Hospital, Salford, UK
10 6.0 Kantonsspital St.Gallen, St. Gallen, Switzerland
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