TICH-3 trial
Tranexamic acid for IntraCerebral Haemorrhage 3


ISRCTN 97695350
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Room S/D2108, Stroke Trials Unit
School of Medicine, University of Nottingham
Queen's Medical Centre, Derby Road
Nottingham NG7 2UH, United Kingdom
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  • Serious Adverse Events (SAEs) — we have a legal responsibility to collect all safety events occurring within the first 7 days after randomisation (including SARs/SUSARs/fatal SAEs).
  • Safety events include: venous thromboembolism; ischaemic events (arterial thrombosis at any site, ischaemic stroke, transient ischaemic attack, peripheral artery embolism, myocardial infarction, acute coronary syndrome) and seizures.
  • Please remember that fatal SAEs need to be reported, even if after 7 days - unless death occurred after discharge from hospital.
  • Please assess if expected according to SmPC.  Expectedness should only be assessed in events that are thought to be possibly/probably/definitely related to the IMP.
  • Investigators have a legal responsibility to report applicable SAEs to the chief investigator without delay, within 24 hours.

Latest recruiting hospitals
Helsinki University Hospital, Helsinki, Finland
Hôpital Foch, Suresnes, France
Aintree University Hospital, Liverpool, UK
Hospital UiTM, Selangor, Malaysia
Hospital Universitario de A Coruña, A Coruña, Spain
Royal Infirmary of Edinburgh, Edinburgh, UK
Craigavon Area Hospital, Portadown, UK
Charing Cross Hospital, London, UK
Kantonsspital St.Gallen, St. Gallen, Switzerland
The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
Bispebjerg Hospital, Copenhagen, Denmark
Hospital Universitari Vall d'Hebron, Barcelona, Spain
Aarhus University Hospital, Aarhus, Denmark
Azienda Ospedalieria di Rilievo Nazionale Antonio Cardarelli, Napoli, Italy
Southampton General Hospital, Southampton, UK
  
Average time to randomisation (last 6 months)
# Hours Hospital
1 1.3 York Hospital, York, UK
2 1.8 Queen's Medical Centre, Nottingham, UK
10 2.0 LTD Pineo Medical Ecosystem, Tbilisi, Georgia
1 2.2 Musgrove Park Hospital, Taunton, UK
1 2.3 King's College Hospital, London, UK
5 2.3 Royal Infirmary of Edinburgh, Edinburgh, UK
3 2.3 Aarhus University Hospital, Aarhus, Denmark
9 2.4 Azienda Ospedalieria di Rilievo Nazionale Antonio Cardarelli, Napoli, Italy
2 2.4 Hospital Sultanah Bahiyah, Kedah, Malaysia
26 2.5 Bispebjerg Hospital, Copenhagen, Denmark
1 2.6 Ipswich Hospital, Ipswich, UK
12 2.6 CHU Lyon, Lyon, France
3 2.6 Basildon University Hospital, Essex, UK
1 2.6 Sunderland Royal Hospital, Tyne and Wear, UK
32 2.6 Helsinki University Hospital, Helsinki, Finland
1 2.6 Royal United Hospital Bath, Bath, UK
11 2.6 St. George's Hospital, London, UK
4 2.6 Eastbourne General District Hospital, Eastbourne, UK
4 2.7 Hôpital André Mignot, Le Chesnay, France
4 2.7 Ninewells Hospital, Dundee, UK
9 2.7 Hospital Universitari Vall d'Hebron, Barcelona, Spain
1 2.8 Fairfield General Hospital, Bury, UK
1 2.8 Queen's Hospital, Romford, UK
5 2.8 Norfolk and Norwich University Hospital, Norwich, UK
15 2.8 ASST Ovest Milanese, Legnano, Italy
2 2.8 Southampton General Hospital, Southampton, UK
1 2.8 Leighton Hospital, Crewe, UK
6 2.9 Derriford Hospital, Plymouth, UK
5 3.0 Royal Victoria Hospital, Belfast, UK
4 3.0 Salford Royal Hospital, Salford, UK
3 3.0 Morriston Hospital, Swansea, UK
4 3.0 Leicester Royal Infirmary, Leicester, UK
4 3.0 King's Mill Hospital, Sutton in Ashfield, UK
11 3.0 Hospital Queen Elizabeth, Sabah, Malaysia
13 3.0 LEPL The First University Clinic of Tbilisi State, Tbilisi, Georgia
6 3.0 Lincoln County Hospital, Lincoln, UK
7 3.0 University Hospital of North Durham, Durham, UK
2 3.1 Hôpital Foch, Suresnes, France
6 3.1 UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
2 3.1 Hospital Universitario de A Coruña, A Coruña, Spain
1 3.1 Uppsala University Hospital, Uppsala, Sweden
8 3.1 Royal Hallamshire Hospital, Sheffield, UK
15 3.1 Kantonsspital St.Gallen, St. Gallen, Switzerland
4 3.2 CHU Rouen, Rouen, France
22 3.2 The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
4 3.2 Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France
12 3.2 New Cross Hospital, Wolverhampton, UK
5 3.2 Hospital Tuanku Jaafar, Seremban, Negeri Sembilan, Malaysia
2 3.2 Arrowe Park Hospital, Wirral, UK
3 3.2 Doncaster Royal Infirmary, Doncaster, UK
4 3.3 Hôpital Nord Laennec, Nantes, France
5 3.3 Hôpital Lariboisière, Paris, France
6 3.3 Hospital Queen Elizabeth II, Sabah, Malaysia
3 3.3 CHU Poitiers, Poitiers, France
4 3.3 Hospital Umum Sarawak, Sarawak, Malaysia
6 3.3 Royal Preston Hospital, Preston, UK
5 3.4 Hull Royal Infirmary, Hull, UK
9 3.4 The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
5 3.4 James Cook University Hospital, Middlesbrough, UK
6 3.4 Hospital Tengku Ampuan Rahimah, Selangor, Malaysia
8 3.4 Hôpital Pierre Paul Riquet, Toulouse, France
5 3.4 Charing Cross Hospital, London, UK
8 3.4 Tallaght University Hospital, Dublin, Republic of Ireland
16 3.4 Centre Hospitalier Sud Francilien, Paris, France
6 3.4 Victoria Hospital, Kirkcaldy, UK
8 3.4 Royal London Hospital, London, UK
7 3.4 ASST di Mantova, Mantova, Italy
8 3.4 Hospital Sultanah Aminah, Johor, Malaysia
4 3.5 Southmead Hospital, Bristol, UK
5 3.5 Cheltenham General Hospital, Cheltenham, UK
4 3.6 Hôpital Roger Salengro, Lille, France
5 3.6 Hospital UiTM, Selangor, Malaysia
2 3.7 University Hospital Coventry, Coventry, UK
3 3.7 Leeds General Infirmary, Leeds, UK
6 3.7 Hôpital Pellegrin Bordeaux, Bordeaux, France
2 3.7 Antrim Area Hospital, Antrim, UK
4 3.7 Craigavon Area Hospital, Portadown, UK
8 3.7 Royal Stoke University Hospital, Stoke-on-Trent, UK
2 3.8 Dorset County Hospital, Dorset, UK
1 3.8 Watford General Hospital, Watford, UK
2 3.9 Southend University Hospital, Essex, UK
2 3.9 Royal Cornwall Hospital, Cornwall, UK
2 3.9 Hospital Pengajar UPM, Serdang Selangor, Malaysia
3 3.9 Addenbrooke's Hospital, Cambridge, UK
1 3.9 Queen Elizabeth Hospital Birmingham, Birmingham, UK
1 3.9 Cumberland Infirmary, Carlisle, UK
7 3.9 Hospital Seberang Jaya, Pulau Pinang, Malaysia
2 3.9 West Suffolk Hospital, Bury St Edmunds, UK
7 4.0 Aberdeen Royal Infirmary, Aberdeen, UK
3 4.0 Luton and Dunstable University Hospital, Luton, UK
2 4.1 University Hospital of North Tees, Stockton on Tees, UK
2 4.2 Royal Devon and Exeter Hospital, Exeter, UK
1 4.4 Royal Derby Hospital, Derby, UK
1 4.4 Kent & Canterbury Hospital, Canterbury, Kent, UK
1 4.4 Northwick Park Hospital, Harrow, UK
1 4.5 Centre Hospitalier Sainte‐Anne, Paris, France
2 4.5 Royal Bournemouth Hospital, Bournemouth, UK
2 4.6 Princess Royal University Hospital, Orpington, UK
6 5.3 Aintree University Hospital, Liverpool, UK
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