TICH-3 trial
Tranexamic acid for IntraCerebral Haemorrhage 3


ISRCTN 97695350
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Room S/D2108, Stroke Trials Unit
School of Medicine, University of Nottingham
Queen's Medical Centre, Derby Road
Nottingham NG7 2UH, United Kingdom
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  • Serious Adverse Events (SAEs) — we have a legal responsibility to collect all safety events occurring within the first 7 days after randomisation (including SARs/SUSARs/fatal SAEs).
  • Safety events include: venous thromboembolism; ischaemic events (arterial thrombosis at any site, ischaemic stroke, transient ischaemic attack, peripheral artery embolism, myocardial infarction, acute coronary syndrome) and seizures.
  • Please remember that fatal SAEs need to be reported, even if after 7 days - unless death occurred after discharge from hospital.
  • Please assess if expected according to RSI.  Expectedness should only be assessed in events that are thought to be possibly/probably/definitely related to the IMP.
  • Investigators have a legal responsibility to report applicable SAEs to the chief investigator without delay, within 24 hours.

Latest recruiting hospitals
Hospital Universitario de A Coruña, A Coruña, Spain
Royal London Hospital, London, UK
CHU Lyon, Lyon, France
The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
Hospital Universitari Vall d'Hebron, Barcelona, Spain
Charing Cross Hospital, London, UK
UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
Aalborg University Hospital, Aalborg, Denmark
Royal Victoria Hospital, Belfast, UK
Centre Hospitalier Sud Francilien, Paris, France
ASST Ovest Milanese, Legnano, Italy
Kent & Canterbury Hospital, Canterbury, Kent, UK
Royal Derby Hospital, Derby, UK
Victoria Hospital, Kirkcaldy, UK
James Cook University Hospital, Middlesbrough, UK
  
Average time to randomisation (last 6 months)
# Hours Hospital
1 0.8 Uppsala University Hospital, Uppsala, Sweden
3 1.9 Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
5 2.1 Aarhus University Hospital, Aarhus, Denmark
3 2.1 LTD Pineo Medical Ecosystem, Tbilisi, Georgia
27 2.2 Bispebjerg Hospital, Copenhagen, Denmark
1 2.3 University Hospitals Monkland, Airdrie, UK
1 2.3 Royal United Hospital Bath, Bath, UK
20 2.3 Helsinki University Hospital, Helsinki, Finland
4 2.3 Royal Victoria Hospital, Belfast, UK
1 2.3 Arrowe Park Hospital, Wirral, UK
5 2.4 Azienda Ospedalieria di Rilievo Nazionale Antonio Cardarelli, Napoli, Italy
1 2.5 Mater Misericordiae University Hospital, Dublin, Republic of Ireland
12 2.5 ASST Ovest Milanese, Legnano, Italy
6 2.6 Odense University Hospital, Odense, Denmark
9 2.6 St. George's Hospital, London, UK
6 2.6 Derriford Hospital, Plymouth, UK
12 2.7 Hospital Universitari Vall d'Hebron, Barcelona, Spain
5 2.7 Royal London Hospital, London, UK
6 2.7 Aberdeen Royal Infirmary, Aberdeen, UK
1 2.7 Hospital UiTM, Selangor, Malaysia
16 2.7 The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
10 2.7 Hospital Universitari de Girona Dr Josep Trueta, Girona, Spain
2 2.8 Hôpital André Mignot, Le Chesnay, France
15 2.8 Hospital Universitario de A Coruña, A Coruña, Spain
4 2.8 Aalborg University Hospital, Aalborg, Denmark
4 2.8 New Cross Hospital, Wolverhampton, UK
1 2.8 Sunderland Royal Hospital, Tyne and Wear, UK
8 2.9 Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France
1 2.9 Kent & Canterbury Hospital, Canterbury, Kent, UK
2 2.9 Lincoln County Hospital, Lincoln, UK
5 3.0 Eastbourne General District Hospital, Eastbourne, UK
11 3.0 CHU Lyon, Lyon, France
1 3.0 Yeovil District Hospital, Somerset, UK
4 3.0 Hospital Queen Elizabeth II, Sabah, Malaysia
6 3.0 Norfolk and Norwich University Hospital, Norwich, UK
8 3.0 Leicester Royal Infirmary, Leicester, UK
6 3.0 Royal Preston Hospital, Preston, UK
1 3.0 Musgrove Park Hospital, Taunton, UK
5 3.1 Cheltenham General Hospital, Cheltenham, UK
1 3.1 Milton Keynes University Hospital, Milton Keynes, UK
5 3.1 Hôpital Foch, Suresnes, France
2 3.1 Whiston Hospital, Merseyside, UK
5 3.1 Royal Stoke University Hospital, Stoke-on-Trent, UK
6 3.1 University Hospital of North Durham, Durham, UK
2 3.2 Hospital Seberang Jaya, Pulau Pinang, Malaysia
8 3.2 LEPL The First University Clinic of Tbilisi State, Tbilisi, Georgia
9 3.2 Presidio Ospedale San Carlo, Milano, Italy
8 3.2 Hôpital Pierre Paul Riquet, Toulouse, France
7 3.2 James Cook University Hospital, Middlesbrough, UK
2 3.3 Hospital Kuala Lumpur, Kuala Lumpur, Malaysia
2 3.3 Watford General Hospital, Watford, UK
2 3.3 Luton and Dunstable University Hospital, Luton, UK
4 3.3 Craigavon Area Hospital, Portadown, UK
20 3.3 The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
14 3.3 UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
4 3.3 Tallaght University Hospital, Dublin, Republic of Ireland
10 3.3 Hospital Queen Elizabeth, Sabah, Malaysia
3 3.4 Southmead Hospital, Bristol, UK
2 3.4 West Suffolk Hospital, Bury St Edmunds, UK
3 3.4 Hôpital Pellegrin Bordeaux, Bordeaux, France
4 3.4 Ninewells Hospital, Dundee, UK
2 3.4 Azienda USL Toscana Nord Ovest, Massa, Italy
1 3.4 CHU Rouen, Rouen, France
8 3.4 Charing Cross Hospital, London, UK
4 3.4 Centre Hospitalier Sainte‐Anne, Paris, France
1 3.4 Aintree University Hospital, Liverpool, UK
2 3.5 Victoria Hospital, Kirkcaldy, UK
5 3.5 King's College Hospital, London, UK
2 3.5 Salford Royal Hospital, Salford, UK
8 3.5 Hôpital Nord Laennec, Nantes, France
4 3.5 York Hospital, York, UK
2 3.6 Hull Royal Infirmary, Hull, UK
6 3.6 Addenbrooke's Hospital, Cambridge, UK
2 3.6 Southampton General Hospital, Southampton, UK
2 3.6 Hôpital Lariboisière, Paris, France
7 3.6 Kantonsspital St.Gallen, St. Gallen, Switzerland
9 3.6 Centre Hospitalier Sud Francilien, Paris, France
7 3.7 Ipswich Hospital, Ipswich, UK
3 3.7 Hôpital Jean Minjoz, Besançon, France
4 3.7 University Hospital of North Tees, Stockton on Tees, UK
2 3.8 Royal Bournemouth Hospital, Bournemouth, UK
5 3.8 Queen's Medical Centre, Nottingham, UK
2 3.8 Royal Infirmary of Edinburgh, Edinburgh, UK
1 3.8 Countess of Chester Hospital, Chester, UK
5 3.9 Morriston Hospital, Swansea, UK
1 3.9 Rigshospitalet, Copenhagen, Denmark
3 3.9 Hôpital Roger Salengro, Lille, France
1 4.0 University Hospital Coventry, Coventry, UK
3 4.0 Royal Derby Hospital, Derby, UK
1 4.1 Royal Cornwall Hospital, Cornwall, UK
4 4.1 Hospital Tengku Ampuan Rahimah, Selangor, Malaysia
2 4.1 University Hospital, Cardiff, UK
2 4.2 Queen Elizabeth Hospital Birmingham, Birmingham, UK
2 4.2 Hospital Sultanah Aminah, Johor, Malaysia
1 4.3 University Hospital Hairmyres, East Kilbride, UK
1 4.3 ASST di Mantova, Mantova, Italy
1 4.4 CHU Poitiers, Poitiers, France
1 4.5 Glan Clwyd Hospital, Denbighshire, UK
1 4.5 Antrim Area Hospital, Antrim, UK
1 4.6 Peterborough City Hospital, Peterborough, UK
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