TICH-3 trial
Tranexamic acid for IntraCerebral Haemorrhage 3


ISRCTN 97695350
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Room S/D2108, Stroke Trials Unit
School of Medicine, University of Nottingham
Queen's Medical Centre, Derby Road
Nottingham NG7 2UH, United Kingdom
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  • Serious Adverse Events (SAEs) — we have a legal responsibility to collect all safety events occurring within the first 7 days after randomisation (including SARs/SUSARs/fatal SAEs).
  • Safety events include: venous thromboembolism; ischaemic events (arterial thrombosis at any site, ischaemic stroke, transient ischaemic attack, peripheral artery embolism, myocardial infarction, acute coronary syndrome) and seizures.
  • Please remember that fatal SAEs need to be reported, even if after 7 days - unless death occurred after discharge from hospital.
  • Please assess if expected according to SmPC.  Expectedness should only be assessed in events that are thought to be possibly/probably/definitely related to the IMP.
  • Investigators have a legal responsibility to report applicable SAEs to the chief investigator without delay, within 24 hours.

Latest recruiting hospitals
Helsinki University Hospital, Helsinki, Finland
Bispebjerg Hospital, Copenhagen, Denmark
ASST Ovest Milanese, Legnano, Italy
King's Mill Hospital, Sutton in Ashfield, UK
Victoria Hospital, Kirkcaldy, UK
Sunderland Royal Hospital, Tyne and Wear, UK
Hôpital Pierre Paul Riquet, Toulouse, France
St. George's Hospital, London, UK
Hospital Sultanah Aminah, Johor, Malaysia
Hospital Seberang Jaya, Pulau Pinang, Malaysia
Centre Hospitalier Sud Francilien, Paris, France
Tallaght University Hospital, Dublin, Republic of Ireland
James Cook University Hospital, Middlesbrough, UK
Azienda Ospedalieria di Rilievo Nazionale Antonio Cardarelli, Napoli, Italy
LEPL The First University Clinic of Tbilisi State, Tbilisi, Georgia
  
Average time to randomisation (last 6 months)
# Hours Hospital
2 1.6 Hôpital Foch, Suresnes, France
2 1.8 Prince Philip Hospital, Llanelli, UK
1 2.0 Hôpital Jean Minjoz, Besançon, France
1 2.2 Musgrove Park Hospital, Taunton, UK
7 2.2 St. George's Hospital, London, UK
1 2.2 Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France
2 2.3 Countess of Chester Hospital, Chester, UK
18 2.3 Bispebjerg Hospital, Copenhagen, Denmark
8 2.4 Azienda Ospedalieria di Rilievo Nazionale Antonio Cardarelli, Napoli, Italy
3 2.4 Royal Victoria Hospital, Belfast, UK
3 2.5 Hospital Sultanah Bahiyah, Kedah, Malaysia
2 2.5 Southend University Hospital, Essex, UK
5 2.5 Hull Royal Infirmary, Hull, UK
3 2.6 Basildon University Hospital, Essex, UK
27 2.6 Helsinki University Hospital, Helsinki, Finland
14 2.6 ASST Ovest Milanese, Legnano, Italy
1 2.6 Sunderland Royal Hospital, Tyne and Wear, UK
6 2.6 CHU Lyon, Lyon, France
5 2.6 LTD Pineo Medical Ecosystem, Tbilisi, Georgia
8 2.7 University Hospital of North Durham, Durham, UK
9 2.7 Hospital Queen Elizabeth II, Sabah, Malaysia
4 2.7 Tallaght University Hospital, Dublin, Republic of Ireland
3 2.8 Antrim Area Hospital, Antrim, UK
11 2.8 UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
6 2.9 Royal Infirmary of Edinburgh, Edinburgh, UK
9 2.9 Hospital Universitari Vall d'Hebron, Barcelona, Spain
8 2.9 Hôpital Nord Laennec, Nantes, France
5 3.0 Salford Royal Hospital, Salford, UK
6 3.0 LEPL The First University Clinic of Tbilisi State, Tbilisi, Georgia
3 3.0 Hôpital Lariboisière, Paris, France
2 3.0 Ninewells Hospital, Dundee, UK
4 3.0 Hôpital André Mignot, Le Chesnay, France
19 3.0 The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
2 3.1 Darent Valley Hospital, Dartford, UK
8 3.1 Royal London Hospital, London, UK
3 3.1 Royal Preston Hospital, Preston, UK
1 3.2 CHU Poitiers, Poitiers, France
6 3.2 Kantonsspital St.Gallen, St. Gallen, Switzerland
2 3.2 York Hospital, York, UK
6 3.2 New Cross Hospital, Wolverhampton, UK
1 3.2 Queen Elizabeth Hospital Birmingham, Birmingham, UK
5 3.2 Aintree University Hospital, Liverpool, UK
3 3.2 Queen's Hospital, Romford, UK
5 3.3 Aberdeen Royal Infirmary, Aberdeen, UK
3 3.3 Norfolk and Norwich University Hospital, Norwich, UK
6 3.3 Addenbrooke's Hospital, Cambridge, UK
4 3.3 Hôpital Roger Salengro, Lille, France
10 3.3 Hospital Queen Elizabeth, Sabah, Malaysia
3 3.3 Cheltenham General Hospital, Cheltenham, UK
5 3.3 Hospital Umum Sarawak, Sarawak, Malaysia
6 3.3 Eastbourne General District Hospital, Eastbourne, UK
1 3.3 Milton Keynes University Hospital, Milton Keynes, UK
4 3.3 Hospital Tengku Ampuan Rahimah, Selangor, Malaysia
8 3.3 Hospital Tuanku Jaafar, Seremban, Negeri Sembilan, Malaysia
7 3.3 Hospital Sultanah Aminah, Johor, Malaysia
5 3.4 The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
7 3.4 Charing Cross Hospital, London, UK
6 3.4 Craigavon Area Hospital, Portadown, UK
3 3.4 Hôpital Pellegrin Bordeaux, Bordeaux, France
7 3.4 King's Mill Hospital, Sutton in Ashfield, UK
7 3.4 Hôpital Pierre Paul Riquet, Toulouse, France
3 3.4 University Hospital of North Tees, Stockton on Tees, UK
4 3.4 ASST di Mantova, Mantova, Italy
4 3.5 Lincoln County Hospital, Lincoln, UK
9 3.5 Centre Hospitalier Sud Francilien, Paris, France
3 3.5 Queen's Medical Centre, Nottingham, UK
2 3.5 Leeds General Infirmary, Leeds, UK
9 3.6 James Cook University Hospital, Middlesbrough, UK
1 3.6 Doncaster Royal Infirmary, Doncaster, UK
1 3.6 Morriston Hospital, Swansea, UK
2 3.6 Leicester Royal Infirmary, Leicester, UK
1 3.6 Derriford Hospital, Plymouth, UK
2 3.6 Arrowe Park Hospital, Wirral, UK
4 3.7 Ipswich Hospital, Ipswich, UK
4 3.7 King's College Hospital, London, UK
2 3.7 Hospital Universiti Sains Malaysia, Kelantan, Malaysia
7 3.7 Victoria Hospital, Kirkcaldy, UK
1 3.7 Royal Derby Hospital, Derby, UK
6 3.7 Southmead Hospital, Bristol, UK
3 3.8 Southampton General Hospital, Southampton, UK
7 3.8 Hospital Seberang Jaya, Pulau Pinang, Malaysia
3 3.8 CHU Rouen, Rouen, France
6 3.8 Royal Stoke University Hospital, Stoke-on-Trent, UK
2 3.9 Dorset County Hospital, Dorset, UK
2 4.0 West Suffolk Hospital, Bury St Edmunds, UK
1 4.0 Hospital Kuala Lumpur, Kuala Lumpur, Malaysia
1 4.1 Hospital Pengajar UPM, Serdang Selangor, Malaysia
3 4.2 Royal Hallamshire Hospital, Sheffield, UK
1 4.2 Yeovil District Hospital, Somerset, UK
2 4.2 Luton and Dunstable University Hospital, Luton, UK
1 4.3 University Hospital Coventry, Coventry, UK
2 4.3 Northwick Park Hospital, Harrow, UK
3 4.4 Royal Bournemouth Hospital, Bournemouth, UK
2 4.5 Hospital UiTM, Selangor, Malaysia
1 4.7 Princess Royal University Hospital, Orpington, UK
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