TICH-3 trial
Tranexamic acid for IntraCerebral Haemorrhage 3


ISRCTN 97695350
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Room S/D2108, Stroke Trials Unit
School of Medicine, University of Nottingham
Queen's Medical Centre, Derby Road
Nottingham NG7 2UH, United Kingdom
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  • Serious Adverse Events (SAEs) — we have a legal responsibility to collect all safety events occurring within the first 7 days after randomisation (including SARs/SUSARs/fatal SAEs).
  • Safety events include: venous thromboembolism; ischaemic events (arterial thrombosis at any site, ischaemic stroke, transient ischaemic attack, peripheral artery embolism, myocardial infarction, acute coronary syndrome) and seizures.
  • Please remember that fatal SAEs need to be reported, even if after 7 days - unless death occurred after discharge from hospital.
  • Please assess if expected according to RSI.  Expectedness should only be assessed in events that are thought to be possibly/probably/definitely related to the IMP.
  • Investigators have a legal responsibility to report applicable SAEs to the chief investigator without delay, within 24 hours.

Latest recruiting hospitals
Hospital Queen Elizabeth, Sabah, Malaysia
Rigshospitalet, Copenhagen, Denmark
ASST Ovest Milanese, Legnano, Italy
Aberdeen Royal Infirmary, Aberdeen, UK
University Hospital of North Tees, Stockton on Tees, UK
Queen's Medical Centre, Nottingham, UK
The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
Royal Victoria Hospital, Belfast, UK
Hull Royal Infirmary, Hull, UK
Hôpital Pierre Paul Riquet, Toulouse, France
Cheltenham General Hospital, Cheltenham, UK
Kantonsspital St.Gallen, St. Gallen, Switzerland
UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
Southampton General Hospital, Southampton, UK
Salford Royal Hospital, Salford, UK
  
Average time to randomisation (last 6 months)
# Hours Hospital
1 0.8 Uppsala University Hospital, Uppsala, Sweden
2 1.7 LTD Pineo Medical Ecosystem, Tbilisi, Georgia
1 1.8 Southend University Hospital, Essex, UK
3 1.9 Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
1 2.3 Royal United Hospital Bath, Bath, UK
6 2.3 Aarhus University Hospital, Aarhus, Denmark
26 2.4 Bispebjerg Hospital, Copenhagen, Denmark
19 2.4 Helsinki University Hospital, Helsinki, Finland
5 2.5 Royal Victoria Hospital, Belfast, UK
3 2.5 Azienda Ospedalieria di Rilievo Nazionale Antonio Cardarelli, Napoli, Italy
5 2.5 Eastbourne General District Hospital, Eastbourne, UK
2 2.6 New Cross Hospital, Wolverhampton, UK
3 2.6 Lincoln County Hospital, Lincoln, UK
5 2.6 Odense University Hospital, Odense, Denmark
16 2.7 The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
6 2.7 Royal London Hospital, London, UK
15 2.7 ASST Ovest Milanese, Legnano, Italy
8 2.7 Aalborg University Hospital, Aalborg, Denmark
13 2.7 CHU Lyon, Lyon, France
9 2.7 St. George's Hospital, London, UK
4 2.7 Norfolk and Norwich University Hospital, Norwich, UK
14 2.7 Hospital Universitario de A Coruña, A Coruña, Spain
2 2.8 Hôpital André Mignot, Le Chesnay, France
2 2.8 University Hospitals Monkland, Airdrie, UK
1 2.8 Sunderland Royal Hospital, Tyne and Wear, UK
15 2.8 Hospital Universitari Vall d'Hebron, Barcelona, Spain
8 2.8 Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France
13 2.9 Hospital Universitari de Girona Dr Josep Trueta, Girona, Spain
7 2.9 Aberdeen Royal Infirmary, Aberdeen, UK
3 2.9 Hospital Sultanah Bahiyah, Kedah, Malaysia
1 2.9 Kent & Canterbury Hospital, Canterbury, Kent, UK
1 3.0 Yeovil District Hospital, Somerset, UK
4 3.0 Hospital Queen Elizabeth II, Sabah, Malaysia
6 3.0 Royal Preston Hospital, Preston, UK
1 3.0 Musgrove Park Hospital, Taunton, UK
1 3.1 Milton Keynes University Hospital, Milton Keynes, UK
10 3.1 Presidio Ospedale San Carlo, Milano, Italy
5 3.1 Southmead Hospital, Bristol, UK
2 3.1 Whiston Hospital, Merseyside, UK
6 3.1 Royal Stoke University Hospital, Stoke-on-Trent, UK
7 3.2 James Cook University Hospital, Middlesbrough, UK
9 3.2 LEPL The First University Clinic of Tbilisi State, Tbilisi, Georgia
7 3.2 Hôpital Nord Laennec, Nantes, France
7 3.2 Leicester Royal Infirmary, Leicester, UK
4 3.2 University Hospital of North Durham, Durham, UK
6 3.2 Hôpital Foch, Suresnes, France
16 3.2 Hospital Queen Elizabeth, Sabah, Malaysia
1 3.3 Hospital Tuanku Jaafar, Seremban, Negeri Sembilan, Malaysia
2 3.3 Watford General Hospital, Watford, UK
5 3.3 Hospital Sultanah Aminah, Johor, Malaysia
3 3.3 Centre Hospitalier Sainte‐Anne, Paris, France
1 3.3 Mater Misericordiae University Hospital, Dublin, Republic of Ireland
3 3.3 Hull Royal Infirmary, Hull, UK
4 3.3 Derriford Hospital, Plymouth, UK
19 3.3 The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
1 3.3 Azienda USL Toscana Nord Ovest, Massa, Italy
4 3.3 Tallaght University Hospital, Dublin, Republic of Ireland
7 3.4 Cheltenham General Hospital, Cheltenham, UK
15 3.4 UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
3 3.4 Hôpital Pellegrin Bordeaux, Bordeaux, France
3 3.4 Hôpital Jean Minjoz, Besançon, France
6 3.4 Queen's Medical Centre, Nottingham, UK
1 3.4 Aintree University Hospital, Liverpool, UK
7 3.4 King's College Hospital, London, UK
5 3.5 Addenbrooke's Hospital, Cambridge, UK
4 3.5 Craigavon Area Hospital, Portadown, UK
7 3.5 Hôpital Pierre Paul Riquet, Toulouse, France
3 3.5 Ninewells Hospital, Dundee, UK
2 3.6 Rigshospitalet, Copenhagen, Denmark
8 3.6 Ipswich Hospital, Ipswich, UK
1 3.6 Southampton General Hospital, Southampton, UK
9 3.6 Kantonsspital St.Gallen, St. Gallen, Switzerland
2 3.6 Hôpital Lariboisière, Paris, France
4 3.6 Hospital Seberang Jaya, Pulau Pinang, Malaysia
6 3.7 Charing Cross Hospital, London, UK
2 3.7 York Hospital, York, UK
5 3.7 Victoria Hospital, Kirkcaldy, UK
5 3.7 Morriston Hospital, Swansea, UK
9 3.7 Centre Hospitalier Sud Francilien, Paris, France
1 3.8 Luton and Dunstable University Hospital, Luton, UK
5 3.8 University Hospital of North Tees, Stockton on Tees, UK
2 3.8 Royal Infirmary of Edinburgh, Edinburgh, UK
3 3.8 Salford Royal Hospital, Salford, UK
1 3.8 Northumbria Specialist Emergency Care Hospital, Northumberland, UK
1 3.8 Countess of Chester Hospital, Chester, UK
2 3.9 ASST di Mantova, Mantova, Italy
2 4.0 West Suffolk Hospital, Bury St Edmunds, UK
3 4.0 Hôpital Roger Salengro, Lille, France
7 4.0 Hospital Tengku Ampuan Rahimah, Selangor, Malaysia
3 4.0 Royal Derby Hospital, Derby, UK
2 4.2 Glan Clwyd Hospital, Denbighshire, UK
2 4.2 Queen Elizabeth Hospital Birmingham, Birmingham, UK
3 4.2 University Hospital, Cardiff, UK
1 4.3 University Hospital Hairmyres, East Kilbride, UK
2 4.4 CHU Rouen, Rouen, France
1 4.4 CHU Poitiers, Poitiers, France
1 4.4 Royal Bournemouth Hospital, Bournemouth, UK
1 4.6 Peterborough City Hospital, Peterborough, UK
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