TICH-3 trial
Tranexamic acid for IntraCerebral Haemorrhage 3


ISRCTN 97695350
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Room S/D2108, Stroke Trials Unit
School of Medicine, University of Nottingham
Queen's Medical Centre, Derby Road
Nottingham NG7 2UH, United Kingdom
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  • Serious Adverse Events (SAEs) — we have a legal responsibility to collect all safety events occurring within the first 7 days after randomisation (including SARs/SUSARs/fatal SAEs).
  • Safety events include: venous thromboembolism; ischaemic events (arterial thrombosis at any site, ischaemic stroke, transient ischaemic attack, peripheral artery embolism, myocardial infarction, acute coronary syndrome) and seizures.
  • Please remember that fatal SAEs need to be reported, even if after 7 days - unless death occurred after discharge from hospital.
  • Please assess if expected according to RSI.  Expectedness should only be assessed in events that are thought to be possibly/probably/definitely related to the IMP.
  • Investigators have a legal responsibility to report applicable SAEs to the chief investigator without delay, within 24 hours.

Latest recruiting hospitals
UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
CHU Lyon, Lyon, France
Hospital Universitari Vall d'Hebron, Barcelona, Spain
Aalborg University Hospital, Gistrup, Denmark
The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
Helsinki University Hospital, Helsinki, Finland
St. George's Hospital, London, UK
Kantonsspital St.Gallen, St. Gallen, Switzerland
Rigshospitalet, Copenhagen, Denmark
Hospital Queen Elizabeth II, Sabah, Malaysia
Royal Devon and Exeter Hospital, Exeter, UK
Royal Infirmary of Edinburgh, Edinburgh, UK
Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France
Hospital Universitari de Girona Dr Josep Trueta, Girona, Spain
Cheltenham General Hospital, Cheltenham, UK
  
Average time to randomisation (last 6 months)
# Hours Hospital
1 1.4 Royal Victoria Hospital, Belfast, UK
5 2.0 Azienda Ospedalieria di Rilievo Nazionale Antonio Cardarelli, Napoli, Italy
17 2.0 Bispebjerg Hospital, Copenhagen, Denmark
2 2.1 Milton Keynes University Hospital, Milton Keynes, UK
1 2.2 Salford Royal Hospital, Salford, UK
4 2.3 Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
8 2.4 Aarhus University Hospital, Aarhus, Denmark
15 2.4 Helsinki University Hospital, Helsinki, Finland
5 2.5 ASST Ovest Milanese, Legnano, Italy
1 2.5 Victoria Hospital, Kirkcaldy, UK
6 2.5 CHU Lyon, Lyon, France
8 2.5 Aalborg University Hospital, Gistrup, Denmark
8 2.6 Northumbria Specialist Emergency Care Hospital, Northumberland, UK
1 2.6 Southampton General Hospital, Southampton, UK
16 2.6 Hospital Universitario de A Coruña, A Coruña, Spain
1 2.6 Cheltenham General Hospital, Cheltenham, UK
4 2.6 Hospital UiTM, Selangor, Malaysia
1 2.6 Doncaster Royal Infirmary, Doncaster, UK
8 2.6 The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
13 2.6 Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France
3 2.7 Hôpital Foch, Suresnes, France
2 2.8 Royal Devon and Exeter Hospital, Exeter, UK
3 2.8 Hôpital Pierre Paul Riquet, Toulouse, France
4 2.8 Ipswich Hospital, Ipswich, UK
2 2.8 Hospital Sultanah Aminah, Johor, Malaysia
2 2.8 Leeds General Infirmary, Leeds, UK
3 2.8 King's Mill Hospital, Sutton in Ashfield, UK
3 2.8 Norfolk and Norwich University Hospital, Norwich, UK
1 2.8 York Hospital, York, UK
4 2.9 Royal Stoke University Hospital, Stoke-on-Trent, UK
4 2.9 Eastbourne General District Hospital, Eastbourne, UK
3 2.9 Southmead Hospital, Bristol, UK
3 2.9 Royal London Hospital, London, UK
8 2.9 Hospital Queen Elizabeth II, Sabah, Malaysia
7 3.0 Presidio Ospedale San Carlo, Milano, Italy
5 3.0 James Cook University Hospital, Middlesbrough, UK
8 3.0 Hospital Universitari Vall d'Hebron, Barcelona, Spain
3 3.0 Whiston Hospital, Merseyside, UK
4 3.0 Hôpital Nord Laennec, Nantes, France
14 3.1 St. George's Hospital, London, UK
2 3.1 Royal Derby Hospital, Derby, UK
8 3.1 Aintree University Hospital, Liverpool, UK
5 3.2 King's College Hospital, London, UK
4 3.2 Charing Cross Hospital, London, UK
3 3.2 Addenbrooke's Hospital, Cambridge, UK
5 3.2 Royal Infirmary of Edinburgh, Edinburgh, UK
5 3.2 Hull Royal Infirmary, Hull, UK
2 3.2 Centre Hospitalier Sainte‐Anne, Paris, France
4 3.3 Hospital Tengku Ampuan Rahimah, Selangor, Malaysia
3 3.3 Leicester Royal Infirmary, Leicester, UK
1 3.3 University Hospital Hairmyres, East Kilbride, UK
2 3.3 Aberdeen Royal Infirmary, Aberdeen, UK
5 3.3 Hospital Universitari de Girona Dr Josep Trueta, Girona, Spain
2 3.3 Hôpital Lariboisière, Paris, France
20 3.3 Hospital Queen Elizabeth, Sabah, Malaysia
1 3.3 Hospital Pengajar UPM, Serdang Selangor, Malaysia
14 3.3 The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
8 3.3 Odense University Hospital, Odense, Denmark
3 3.4 Kent & Canterbury Hospital, Canterbury, Kent, UK
4 3.4 CHU Rouen, Rouen, France
1 3.4 Royal Cornwall Hospital, Cornwall, UK
1 3.4 Morriston Hospital, Swansea, UK
2 3.4 Royal Bournemouth Hospital, Bournemouth, UK
4 3.5 Hospital Seberang Jaya, Pulau Pinang, Malaysia
5 3.5 University Hospital, Cardiff, UK
1 3.5 Rigshospitalet, Copenhagen, Denmark
5 3.5 Hôpital Pellegrin Bordeaux, Bordeaux, France
10 3.6 Hospital Sultanah Bahiyah, Kedah, Malaysia
4 3.6 Hôpital André Mignot, Le Chesnay, France
4 3.6 Centre Hospitalier Sud Francilien, Paris, France
2 3.6 Peterborough City Hospital, Peterborough, UK
3 3.7 Watford General Hospital, Watford, UK
1 3.7 Queen's Hospital, Romford, UK
2 3.7 University Hospital of North Durham, Durham, UK
1 3.8 Hospital Tuanku Jaafar, Seremban, Negeri Sembilan, Malaysia
2 3.8 Derriford Hospital, Plymouth, UK
2 3.8 Lincoln County Hospital, Lincoln, UK
2 3.8 Glan Clwyd Hospital, Denbighshire, UK
1 3.8 Ninewells Hospital, Dundee, UK
9 3.9 UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
4 3.9 Queen's Medical Centre, Nottingham, UK
1 3.9 Antrim Area Hospital, Antrim, UK
2 3.9 Basildon University Hospital, Essex, UK
4 4.0 New Cross Hospital, Wolverhampton, UK
2 4.0 Craigavon Area Hospital, Portadown, UK
1 4.0 Royal United Hospital Bath, Bath, UK
2 4.0 West Suffolk Hospital, Bury St Edmunds, UK
1 4.1 Hôpital Jean Minjoz, Besançon, France
2 4.2 University Hospitals Monkland, Airdrie, UK
1 4.2 Royal Preston Hospital, Preston, UK
2 4.3 Fairfield General Hospital, Bury, UK
1 4.3 Yeovil District Hospital, Somerset, UK
1 4.5 Bradford Royal Infirmary, Bradford, UK
10 5.8 Kantonsspital St.Gallen, St. Gallen, Switzerland
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