TICH-3 trial
Tranexamic acid for IntraCerebral Haemorrhage 3


ISRCTN 97695350
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Room S/D2108, Stroke Trials Unit
School of Medicine, University of Nottingham
Queen's Medical Centre, Derby Road
Nottingham NG7 2UH, United Kingdom
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  • Serious Adverse Events (SAEs) — we have a legal responsibility to collect all safety events occurring within the first 7 days after randomisation (including SARs/SUSARs/fatal SAEs).
  • Safety events include: venous thromboembolism; ischaemic events (arterial thrombosis at any site, ischaemic stroke, transient ischaemic attack, peripheral artery embolism, myocardial infarction, acute coronary syndrome) and seizures.
  • Please remember that fatal SAEs need to be reported, even if after 7 days - unless death occurred after discharge from hospital.
  • Please assess if expected according to RSI.  Expectedness should only be assessed in events that are thought to be possibly/probably/definitely related to the IMP.
  • Investigators have a legal responsibility to report applicable SAEs to the chief investigator without delay, within 24 hours.

Latest recruiting hospitals
Derriford Hospital, Plymouth, UK
Ninewells Hospital, Dundee, UK
Kent & Canterbury Hospital, Canterbury, Kent, UK
Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
CHU Rouen, Rouen, France
Hospital Universitari de Girona Dr Josep Trueta, Girona, Spain
Aalborg University Hospital, Gistrup, Denmark
Fairfield General Hospital, Bury, UK
Royal Derby Hospital, Derby, UK
Bispebjerg Hospital, Copenhagen, Denmark
The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
University Hospitals Monkland, Airdrie, UK
Leeds General Infirmary, Leeds, UK
Hospital Queen Elizabeth II, Sabah, Malaysia
Whiston Hospital, Merseyside, UK
  
Average time to randomisation (last 6 months)
# Hours Hospital
1 0.8 Uppsala University Hospital, Uppsala, Sweden
1 0.8 Hospital UiTM, Selangor, Malaysia
1 1.5 LTD Pineo Medical Ecosystem, Tbilisi, Georgia
1 1.8 Southend University Hospital, Essex, UK
1 2.0 Azienda USL Toscana Nord Ovest, Massa, Italy
5 2.2 Aarhus University Hospital, Aarhus, Denmark
4 2.2 Royal Victoria Hospital, Belfast, UK
2 2.2 Norfolk and Norwich University Hospital, Norwich, UK
5 2.2 Azienda Ospedalieria di Rilievo Nazionale Antonio Cardarelli, Napoli, Italy
5 2.3 Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
4 2.3 Royal London Hospital, London, UK
13 2.4 Aalborg University Hospital, Gistrup, Denmark
1 2.4 Milton Keynes University Hospital, Milton Keynes, UK
19 2.5 Helsinki University Hospital, Helsinki, Finland
13 2.5 ASST Ovest Milanese, Legnano, Italy
5 2.5 Eastbourne General District Hospital, Eastbourne, UK
3 2.6 Lincoln County Hospital, Lincoln, UK
11 2.7 The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
13 2.7 Hospital Universitario de A Coruña, A Coruña, Spain
7 2.7 Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France
11 2.7 CHU Lyon, Lyon, France
22 2.7 Bispebjerg Hospital, Copenhagen, Denmark
3 2.7 Leeds General Infirmary, Leeds, UK
1 2.8 Sunderland Royal Hospital, Tyne and Wear, UK
4 2.8 Leicester Royal Infirmary, Leicester, UK
6 2.9 Aberdeen Royal Infirmary, Aberdeen, UK
9 2.9 Hôpital Nord Laennec, Nantes, France
5 2.9 Royal Preston Hospital, Preston, UK
5 2.9 Southmead Hospital, Bristol, UK
8 3.0 Odense University Hospital, Odense, Denmark
1 3.0 Musgrove Park Hospital, Taunton, UK
4 3.0 Whiston Hospital, Merseyside, UK
8 3.0 St. George's Hospital, London, UK
3 3.1 Hospital Queen Elizabeth II, Sabah, Malaysia
3 3.1 Kent & Canterbury Hospital, Canterbury, Kent, UK
14 3.1 Hospital Universitari de Girona Dr Josep Trueta, Girona, Spain
6 3.1 James Cook University Hospital, Middlesbrough, UK
4 3.1 Hôpital Foch, Suresnes, France
10 3.1 Hospital Universitari Vall d'Hebron, Barcelona, Spain
2 3.2 Ninewells Hospital, Dundee, UK
2 3.2 Aintree University Hospital, Liverpool, UK
6 3.2 Presidio Ospedale San Carlo, Milano, Italy
4 3.2 New Cross Hospital, Wolverhampton, UK
23 3.2 Hospital Queen Elizabeth, Sabah, Malaysia
6 3.2 Hospital Sultanah Bahiyah, Kedah, Malaysia
3 3.2 University Hospitals Monkland, Airdrie, UK
6 3.2 Hospital Sultanah Aminah, Johor, Malaysia
2 3.3 Watford General Hospital, Watford, UK
2 3.3 Royal Infirmary of Edinburgh, Edinburgh, UK
4 3.3 Northumbria Specialist Emergency Care Hospital, Northumberland, UK
5 3.3 Royal Stoke University Hospital, Stoke-on-Trent, UK
1 3.3 Mater Misericordiae University Hospital, Dublin, Republic of Ireland
3 3.3 Rigshospitalet, Copenhagen, Denmark
5 3.3 LEPL The First University Clinic of Tbilisi State, Tbilisi, Georgia
4 3.3 Addenbrooke's Hospital, Cambridge, UK
5 3.3 Victoria Hospital, Kirkcaldy, UK
3 3.3 Hull Royal Infirmary, Hull, UK
4 3.3 Tallaght University Hospital, Dublin, Republic of Ireland
8 3.3 Hôpital Pierre Paul Riquet, Toulouse, France
4 3.4 Cheltenham General Hospital, Cheltenham, UK
17 3.4 The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
1 3.4 York Hospital, York, UK
18 3.4 UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
5 3.4 Charing Cross Hospital, London, UK
2 3.4 King's Mill Hospital, Sutton in Ashfield, UK
3 3.5 Royal Derby Hospital, Derby, UK
2 3.5 Hospital Tuanku Jaafar, Seremban, Negeri Sembilan, Malaysia
6 3.5 Ipswich Hospital, Ipswich, UK
1 3.6 Southampton General Hospital, Southampton, UK
3 3.6 Hôpital Pellegrin Bordeaux, Bordeaux, France
6 3.6 Hospital Tengku Ampuan Rahimah, Selangor, Malaysia
6 3.6 King's College Hospital, London, UK
8 3.7 Queen's Medical Centre, Nottingham, UK
1 3.8 Luton and Dunstable University Hospital, Luton, UK
2 3.8 University Hospital Hairmyres, East Kilbride, UK
9 3.8 Centre Hospitalier Sud Francilien, Paris, France
4 3.8 University Hospital, Cardiff, UK
4 3.8 Morriston Hospital, Swansea, UK
3 3.8 Hôpital Lariboisière, Paris, France
2 3.8 Hôpital Roger Salengro, Lille, France
2 3.9 Hôpital Jean Minjoz, Besançon, France
1 3.9 Antrim Area Hospital, Antrim, UK
1 3.9 University Hospital of North Durham, Durham, UK
3 4.0 University Hospital of North Tees, Stockton on Tees, UK
3 4.0 ASST di Mantova, Mantova, Italy
3 4.0 West Suffolk Hospital, Bury St Edmunds, UK
1 4.0 Royal United Hospital Bath, Bath, UK
4 4.0 CHU Rouen, Rouen, France
3 4.1 Derriford Hospital, Plymouth, UK
1 4.1 Fairfield General Hospital, Bury, UK
1 4.1 Craigavon Area Hospital, Portadown, UK
2 4.2 Glan Clwyd Hospital, Denbighshire, UK
3 4.2 Hospital Seberang Jaya, Pulau Pinang, Malaysia
1 4.3 Queen Elizabeth Hospital Birmingham, Birmingham, UK
1 4.3 Peterborough City Hospital, Peterborough, UK
1 4.5 Salford Royal Hospital, Salford, UK
1 4.5 Bradford Royal Infirmary, Bradford, UK
10 6.0 Kantonsspital St.Gallen, St. Gallen, Switzerland
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