TICH-3 trial
Tranexamic acid for IntraCerebral Haemorrhage 3


ISRCTN 97695350
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Room S/D2108, Stroke Trials Unit
School of Medicine, University of Nottingham
Queen's Medical Centre, Derby Road
Nottingham NG7 2UH, United Kingdom
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  • Serious Adverse Events (SAEs) — we have a legal responsibility to collect all safety events occurring within the first 7 days after randomisation (including SARs/SUSARs/fatal SAEs).
  • Safety events include: venous thromboembolism; ischaemic events (arterial thrombosis at any site, ischaemic stroke, transient ischaemic attack, peripheral artery embolism, myocardial infarction, acute coronary syndrome) and seizures.
  • Please remember that fatal SAEs need to be reported, even if after 7 days - unless death occurred after discharge from hospital.
  • Please assess if expected according to RSI.  Expectedness should only be assessed in events that are thought to be possibly/probably/definitely related to the IMP.
  • Investigators have a legal responsibility to report applicable SAEs to the chief investigator without delay, within 24 hours.

Latest recruiting hospitals
Salford Royal Hospital, Salford, UK
Aalborg University Hospital, Gistrup, Denmark
Hospital Universitari de Girona Dr Josep Trueta, Girona, Spain
Helsinki University Hospital, Helsinki, Finland
Kent & Canterbury Hospital, Canterbury, Kent, UK
Royal Derby Hospital, Derby, UK
CHU Rouen, Rouen, France
Mater Misericordiae University Hospital, Dublin, Republic of Ireland
Hospital Queen Elizabeth, Sabah, Malaysia
Doncaster Royal Infirmary, Doncaster, UK
ASST Ovest Milanese, Legnano, Italy
Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
Ipswich Hospital, Ipswich, UK
  
Average time to randomisation (last 6 months)
# Hours Hospital
1 1.6 Southmead Hospital, Bristol, UK
1 1.6 King's Mill Hospital, Sutton in Ashfield, UK
4 1.9 Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
5 1.9 Azienda Ospedalieria di Rilievo Nazionale Antonio Cardarelli, Napoli, Italy
22 2.0 Bispebjerg Hospital, Copenhagen, Denmark
2 2.2 Mater Misericordiae University Hospital, Dublin, Republic of Ireland
1 2.3 Hôpital Pierre Paul Riquet, Toulouse, France
1 2.3 Hôpital Lariboisière, Paris, France
1 2.4 Hospital Sultanah Aminah, Johor, Malaysia
8 2.4 Aalborg University Hospital, Gistrup, Denmark
1 2.4 Leeds General Infirmary, Leeds, UK
7 2.4 Aarhus University Hospital, Aarhus, Denmark
2 2.5 Victoria Hospital, Kirkcaldy, UK
10 2.6 The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
1 2.6 Southampton General Hospital, Southampton, UK
13 2.6 Helsinki University Hospital, Helsinki, Finland
6 2.6 Northumbria Specialist Emergency Care Hospital, Northumberland, UK
3 2.6 CHU Lyon, Lyon, France
1 2.6 Cheltenham General Hospital, Cheltenham, UK
3 2.6 Whiston Hospital, Merseyside, UK
13 2.7 Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France
2 2.7 Milton Keynes University Hospital, Milton Keynes, UK
4 2.7 Royal Stoke University Hospital, Stoke-on-Trent, UK
4 2.7 Ipswich Hospital, Ipswich, UK
4 2.7 Centre Hospitalier Sainte‐Anne, Paris, France
2 2.8 Royal Devon and Exeter Hospital, Exeter, UK
16 2.8 Hospital Universitario de A Coruña, A Coruña, Spain
3 2.8 Norfolk and Norwich University Hospital, Norwich, UK
1 2.8 York Hospital, York, UK
5 2.8 Hull Royal Infirmary, Hull, UK
8 2.9 ASST Ovest Milanese, Legnano, Italy
13 2.9 St. George's Hospital, London, UK
3 2.9 Eastbourne General District Hospital, Eastbourne, UK
3 2.9 Royal London Hospital, London, UK
8 2.9 Hospital Queen Elizabeth II, Sabah, Malaysia
1 3.0 CHU Poitiers, Poitiers, France
7 3.0 Presidio Ospedale San Carlo, Milano, Italy
3 3.0 Salford Royal Hospital, Salford, UK
2 3.1 Aberdeen Royal Infirmary, Aberdeen, UK
7 3.1 Kantonsspital St.Gallen, St. Gallen, Switzerland
6 3.1 King's College Hospital, London, UK
9 3.1 Aintree University Hospital, Liverpool, UK
6 3.2 James Cook University Hospital, Middlesbrough, UK
2 3.2 University Hospital Coventry, Coventry, UK
5 3.2 Hospital Seberang Jaya, Pulau Pinang, Malaysia
19 3.2 Hospital Queen Elizabeth, Sabah, Malaysia
2 3.2 Royal Preston Hospital, Preston, UK
5 3.2 CHU Rouen, Rouen, France
6 3.2 Hospital Universitari Vall d'Hebron, Barcelona, Spain
3 3.3 Charing Cross Hospital, London, UK
2 3.3 Leicester Royal Infirmary, Leicester, UK
2 3.3 Hôpital Nord Laennec, Nantes, France
1 3.3 Hospital Pengajar UPM, Serdang Selangor, Malaysia
4 3.3 Hospital UiTM, Selangor, Malaysia
19 3.3 The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
3 3.4 Royal Derby Hospital, Derby, UK
2 3.4 Doncaster Royal Infirmary, Doncaster, UK
5 3.4 Kent & Canterbury Hospital, Canterbury, Kent, UK
1 3.4 Royal Cornwall Hospital, Cornwall, UK
2 3.4 Royal Bournemouth Hospital, Bournemouth, UK
2 3.5 Hôpital Pellegrin Bordeaux, Bordeaux, France
5 3.5 Hôpital André Mignot, Le Chesnay, France
1 3.5 Rigshospitalet, Copenhagen, Denmark
3 3.5 Basildon University Hospital, Essex, UK
4 3.5 Odense University Hospital, Odense, Denmark
5 3.5 Queen's Medical Centre, Nottingham, UK
3 3.6 Addenbrooke's Hospital, Cambridge, UK
8 3.6 Hospital Sultanah Bahiyah, Kedah, Malaysia
3 3.6 Hospital Tengku Ampuan Rahimah, Selangor, Malaysia
2 3.6 Peterborough City Hospital, Peterborough, UK
5 3.6 Hospital Universitari de Girona Dr Josep Trueta, Girona, Spain
3 3.7 Derriford Hospital, Plymouth, UK
3 3.7 Watford General Hospital, Watford, UK
1 3.7 Queen's Hospital, Romford, UK
2 3.7 University Hospital of North Durham, Durham, UK
5 3.8 University Hospital, Cardiff, UK
2 3.8 Lincoln County Hospital, Lincoln, UK
1 3.8 Ninewells Hospital, Dundee, UK
7 3.9 UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
3 4.0 Glan Clwyd Hospital, Denbighshire, UK
2 4.0 Craigavon Area Hospital, Portadown, UK
1 4.0 Hôpital Foch, Suresnes, France
2 4.0 West Suffolk Hospital, Bury St Edmunds, UK
1 4.1 Hôpital Jean Minjoz, Besançon, France
3 4.2 New Cross Hospital, Wolverhampton, UK
3 4.3 University Hospitals Monkland, Airdrie, UK
2 4.3 Fairfield General Hospital, Bury, UK
1 4.3 Yeovil District Hospital, Somerset, UK
1 4.4 Centre Hospitalier Sud Francilien, Paris, France
5 6.7 Royal Infirmary of Edinburgh, Edinburgh, UK
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