TICH-3 trial
Tranexamic acid for IntraCerebral Haemorrhage 3


ISRCTN 97695350
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Room S/D2108, Stroke Trials Unit
School of Medicine, University of Nottingham
Queen's Medical Centre, Derby Road
Nottingham NG7 2UH, United Kingdom
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  • Serious Adverse Events (SAEs) — we have a legal responsibility to collect all safety events occurring within the first 7 days after randomisation (including SARs/SUSARs/fatal SAEs).
  • Safety events include: venous thromboembolism; ischaemic events (arterial thrombosis at any site, ischaemic stroke, transient ischaemic attack, peripheral artery embolism, myocardial infarction, acute coronary syndrome) and seizures.
  • Please remember that fatal SAEs need to be reported, even if after 7 days - unless death occurred after discharge from hospital.
  • Please assess if expected according to RSI.  Expectedness should only be assessed in events that are thought to be possibly/probably/definitely related to the IMP.
  • Investigators have a legal responsibility to report applicable SAEs to the chief investigator without delay, within 24 hours.

Latest recruiting hospitals
Basildon University Hospital, Essex, UK
Hospital Universitari Vall d'Hebron, Barcelona, Spain
Eastbourne General District Hospital, Eastbourne, UK
Hôpital Pellegrin Bordeaux, Bordeaux, France
Hospital UiTM, Selangor, Malaysia
Hospital Universitario de A Coruña, A Coruña, Spain
UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
Bispebjerg Hospital, Copenhagen, Denmark
The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
Leicester Royal Infirmary, Leicester, UK
Hospital Queen Elizabeth II, Sabah, Malaysia
Craigavon Area Hospital, Portadown, UK
The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
Royal Bournemouth Hospital, Bournemouth, UK
Helsinki University Hospital, Helsinki, Finland
  
Average time to randomisation (last 6 months)
# Hours Hospital
1 1.8 Southend University Hospital, Essex, UK
7 2.0 Azienda Ospedalieria di Rilievo Nazionale Antonio Cardarelli, Napoli, Italy
1 2.0 Azienda USL Toscana Nord Ovest, Massa, Italy
22 2.1 Bispebjerg Hospital, Copenhagen, Denmark
3 2.3 Hospital UiTM, Selangor, Malaysia
4 2.3 Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
12 2.3 Aalborg University Hospital, Gistrup, Denmark
3 2.3 Royal Victoria Hospital, Belfast, UK
15 2.4 Helsinki University Hospital, Helsinki, Finland
4 2.4 Aarhus University Hospital, Aarhus, Denmark
1 2.4 Milton Keynes University Hospital, Milton Keynes, UK
11 2.6 ASST Ovest Milanese, Legnano, Italy
5 2.6 Eastbourne General District Hospital, Eastbourne, UK
2 2.6 Tallaght University Hospital, Dublin, Republic of Ireland
3 2.6 Ipswich Hospital, Ipswich, UK
1 2.6 Doncaster Royal Infirmary, Doncaster, UK
4 2.6 Royal London Hospital, London, UK
11 2.7 The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
5 2.7 Hospital Sultanah Aminah, Johor, Malaysia
11 2.7 CHU Lyon, Lyon, France
3 2.7 Hôpital Foch, Suresnes, France
3 2.7 Leeds General Infirmary, Leeds, UK
9 2.8 Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France
5 2.8 Southmead Hospital, Bristol, UK
15 2.8 Hospital Universitario de A Coruña, A Coruña, Spain
8 2.8 Northumbria Specialist Emergency Care Hospital, Northumberland, UK
7 2.8 Presidio Ospedale San Carlo, Milano, Italy
6 2.9 Royal Stoke University Hospital, Stoke-on-Trent, UK
1 2.9 Royal Infirmary of Edinburgh, Edinburgh, UK
8 3.0 Hôpital Nord Laennec, Nantes, France
2 3.0 Rigshospitalet, Copenhagen, Denmark
6 3.0 Leicester Royal Infirmary, Leicester, UK
3 3.0 Whiston Hospital, Merseyside, UK
12 3.0 St. George's Hospital, London, UK
3 3.1 Addenbrooke's Hospital, Cambridge, UK
2 3.1 Royal Derby Hospital, Derby, UK
2 3.1 Southampton General Hospital, Southampton, UK
7 3.1 Aintree University Hospital, Liverpool, UK
2 3.1 York Hospital, York, UK
9 3.1 Hospital Universitari Vall d'Hebron, Barcelona, Spain
5 3.1 Kent & Canterbury Hospital, Canterbury, Kent, UK
22 3.1 Hospital Queen Elizabeth, Sabah, Malaysia
2 3.2 Watford General Hospital, Watford, UK
1 3.2 Hôpital André Mignot, Le Chesnay, France
4 3.2 Charing Cross Hospital, London, UK
11 3.2 Hospital Universitari de Girona Dr Josep Trueta, Girona, Spain
1 3.2 Hôpital Roger Salengro, Lille, France
2 3.2 Norfolk and Norwich University Hospital, Norwich, UK
5 3.2 Hull Royal Infirmary, Hull, UK
1 3.3 University Hospital Hairmyres, East Kilbride, UK
1 3.3 Mater Misericordiae University Hospital, Dublin, Republic of Ireland
18 3.3 The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
5 3.3 Hôpital Pierre Paul Riquet, Toulouse, France
4 3.3 Lincoln County Hospital, Lincoln, UK
5 3.3 Victoria Hospital, Kirkcaldy, UK
2 3.3 Salford Royal Hospital, Salford, UK
4 3.3 James Cook University Hospital, Middlesbrough, UK
8 3.3 Odense University Hospital, Odense, Denmark
2 3.4 Morriston Hospital, Swansea, UK
2 3.4 King's Mill Hospital, Sutton in Ashfield, UK
1 3.4 Royal Cornwall Hospital, Cornwall, UK
2 3.4 Royal Bournemouth Hospital, Bournemouth, UK
5 3.5 Hospital Tengku Ampuan Rahimah, Selangor, Malaysia
2 3.5 Hospital Tuanku Jaafar, Seremban, Negeri Sembilan, Malaysia
11 3.5 Hospital Sultanah Bahiyah, Kedah, Malaysia
5 3.5 Hôpital Pellegrin Bordeaux, Bordeaux, France
4 3.5 Hospital Queen Elizabeth II, Sabah, Malaysia
6 3.6 King's College Hospital, London, UK
2 3.6 Peterborough City Hospital, Peterborough, UK
7 3.7 Queen's Medical Centre, Nottingham, UK
4 3.7 Hospital Seberang Jaya, Pulau Pinang, Malaysia
6 3.7 Centre Hospitalier Sud Francilien, Paris, France
1 3.8 Luton and Dunstable University Hospital, Luton, UK
13 3.8 UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
3 3.8 Glan Clwyd Hospital, Denbighshire, UK
1 3.8 Ninewells Hospital, Dundee, UK
2 3.9 Aberdeen Royal Infirmary, Aberdeen, UK
1 3.9 Antrim Area Hospital, Antrim, UK
3 3.9 New Cross Hospital, Wolverhampton, UK
3 3.9 University Hospitals Monkland, Airdrie, UK
4 3.9 University Hospital, Cardiff, UK
2 3.9 Basildon University Hospital, Essex, UK
3 3.9 Hôpital Jean Minjoz, Besançon, France
1 4.0 Centre Hospitalier Sainte‐Anne, Paris, France
3 4.0 ASST di Mantova, Mantova, Italy
1 4.0 Royal United Hospital Bath, Bath, UK
3 4.0 Craigavon Area Hospital, Portadown, UK
4 4.0 CHU Rouen, Rouen, France
3 4.0 Derriford Hospital, Plymouth, UK
2 4.1 University Hospital of North Tees, Stockton on Tees, UK
1 4.1 Fairfield General Hospital, Bury, UK
4 4.1 West Suffolk Hospital, Bury St Edmunds, UK
2 4.1 Cheltenham General Hospital, Cheltenham, UK
2 4.1 Hôpital Lariboisière, Paris, France
1 4.2 Royal Preston Hospital, Preston, UK
1 4.5 Bradford Royal Infirmary, Bradford, UK
1 4.6 University Hospital of North Durham, Durham, UK
10 5.9 Kantonsspital St.Gallen, St. Gallen, Switzerland
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