TICH-3 trial
Tranexamic acid for IntraCerebral Haemorrhage 3


ISRCTN 97695350
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Room S/D2108, Stroke Trials Unit
School of Medicine, University of Nottingham
Queen's Medical Centre, Derby Road
Nottingham NG7 2UH, United Kingdom
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  • Serious Adverse Events (SAEs) — we have a legal responsibility to collect all safety events occurring within the first 7 days after randomisation (including SARs/SUSARs/fatal SAEs).
  • Safety events include: venous thromboembolism; ischaemic events (arterial thrombosis at any site, ischaemic stroke, transient ischaemic attack, peripheral artery embolism, myocardial infarction, acute coronary syndrome) and seizures.
  • Please remember that fatal SAEs need to be reported, even if after 7 days - unless death occurred after discharge from hospital.
  • Please assess if expected according to RSI.  Expectedness should only be assessed in events that are thought to be possibly/probably/definitely related to the IMP.
  • Investigators have a legal responsibility to report applicable SAEs to the chief investigator without delay, within 24 hours.

Latest recruiting hospitals
King's College Hospital, London, UK
Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France
Presidio Ospedale San Carlo, Milano, Italy
Watford General Hospital, Watford, UK
Hospital Universitario de A Coruña, A Coruña, Spain
UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
Helsinki University Hospital, Helsinki, Finland
Northumbria Specialist Emergency Care Hospital, Northumberland, UK
University Hospital, Cardiff, UK
Aarhus University Hospital, Aarhus, Denmark
Aintree University Hospital, Liverpool, UK
Royal Infirmary of Edinburgh, Edinburgh, UK
Hospital Tengku Ampuan Rahimah, Selangor, Malaysia
Hospital Queen Elizabeth II, Sabah, Malaysia
Uppsala University Hospital, Uppsala, Sweden
  
Average time to randomisation (last 6 months)
# Hours Hospital
1 1.8 Southend University Hospital, Essex, UK
5 1.8 Azienda Ospedalieria di Rilievo Nazionale Antonio Cardarelli, Napoli, Italy
1 2.0 Azienda USL Toscana Nord Ovest, Massa, Italy
24 2.1 Bispebjerg Hospital, Copenhagen, Denmark
10 2.2 Aalborg University Hospital, Gistrup, Denmark
3 2.3 Hospital UiTM, Selangor, Malaysia
9 2.3 Aarhus University Hospital, Aarhus, Denmark
2 2.4 Royal Victoria Hospital, Belfast, UK
1 2.4 Milton Keynes University Hospital, Milton Keynes, UK
3 2.4 Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
8 2.5 CHU Lyon, Lyon, France
16 2.5 Helsinki University Hospital, Helsinki, Finland
11 2.6 Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France
5 2.6 Eastbourne General District Hospital, Eastbourne, UK
10 2.6 The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
2 2.6 Royal Infirmary of Edinburgh, Edinburgh, UK
3 2.6 Ipswich Hospital, Ipswich, UK
1 2.6 Doncaster Royal Infirmary, Doncaster, UK
10 2.6 ASST Ovest Milanese, Legnano, Italy
14 2.7 Hospital Universitario de A Coruña, A Coruña, Spain
5 2.7 Hospital Sultanah Aminah, Johor, Malaysia
2 2.7 Addenbrooke's Hospital, Cambridge, UK
9 2.7 Northumbria Specialist Emergency Care Hospital, Northumberland, UK
3 2.7 Leeds General Infirmary, Leeds, UK
5 2.8 Southmead Hospital, Bristol, UK
3 2.8 Norfolk and Norwich University Hospital, Norwich, UK
1 2.8 Royal Derby Hospital, Derby, UK
7 2.8 Presidio Ospedale San Carlo, Milano, Italy
4 2.9 Royal Stoke University Hospital, Stoke-on-Trent, UK
5 2.9 James Cook University Hospital, Middlesbrough, UK
3 2.9 Royal London Hospital, London, UK
7 3.0 Hôpital Nord Laennec, Nantes, France
2 3.0 Rigshospitalet, Copenhagen, Denmark
3 3.0 Whiston Hospital, Merseyside, UK
4 3.0 Hôpital Foch, Suresnes, France
6 3.0 Hospital Queen Elizabeth II, Sabah, Malaysia
6 3.1 King's College Hospital, London, UK
2 3.1 Southampton General Hospital, Southampton, UK
11 3.1 St. George's Hospital, London, UK
8 3.1 Aintree University Hospital, Liverpool, UK
2 3.1 York Hospital, York, UK
4 3.2 Charing Cross Hospital, London, UK
4 3.2 Kent & Canterbury Hospital, Canterbury, Kent, UK
8 3.2 Hospital Universitari Vall d'Hebron, Barcelona, Spain
7 3.2 Hospital Universitari de Girona Dr Josep Trueta, Girona, Spain
5 3.2 Leicester Royal Infirmary, Leicester, UK
15 3.2 The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
24 3.2 Hospital Queen Elizabeth, Sabah, Malaysia
3 3.2 Lincoln County Hospital, Lincoln, UK
1 3.2 Hôpital Roger Salengro, Lille, France
5 3.2 Hull Royal Infirmary, Hull, UK
1 3.3 University Hospital Hairmyres, East Kilbride, UK
1 3.3 Mater Misericordiae University Hospital, Dublin, Republic of Ireland
1 3.3 Royal Devon and Exeter Hospital, Exeter, UK
2 3.3 Hôpital Lariboisière, Paris, France
1 3.3 Hospital Pengajar UPM, Serdang Selangor, Malaysia
5 3.3 Hôpital Pierre Paul Riquet, Toulouse, France
2 3.3 Salford Royal Hospital, Salford, UK
8 3.3 Odense University Hospital, Odense, Denmark
2 3.4 Morriston Hospital, Swansea, UK
2 3.4 King's Mill Hospital, Sutton in Ashfield, UK
3 3.4 Watford General Hospital, Watford, UK
1 3.4 Royal Cornwall Hospital, Cornwall, UK
2 3.4 Royal Bournemouth Hospital, Bournemouth, UK
4 3.5 Victoria Hospital, Kirkcaldy, UK
11 3.5 Hospital Sultanah Bahiyah, Kedah, Malaysia
5 3.5 Hôpital Pellegrin Bordeaux, Bordeaux, France
7 3.5 Hospital Tengku Ampuan Rahimah, Selangor, Malaysia
2 3.6 Peterborough City Hospital, Peterborough, UK
7 3.7 Queen's Medical Centre, Nottingham, UK
6 3.7 Hospital Seberang Jaya, Pulau Pinang, Malaysia
5 3.7 Centre Hospitalier Sud Francilien, Paris, France
2 3.7 Hôpital Jean Minjoz, Besançon, France
1 3.8 Luton and Dunstable University Hospital, Luton, UK
5 3.8 CHU Rouen, Rouen, France
13 3.8 UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
1 3.8 Hospital Tuanku Jaafar, Seremban, Negeri Sembilan, Malaysia
2 3.8 ASST di Mantova, Mantova, Italy
3 3.8 Glan Clwyd Hospital, Denbighshire, UK
1 3.8 Ninewells Hospital, Dundee, UK
2 3.8 Hôpital André Mignot, Le Chesnay, France
2 3.9 Aberdeen Royal Infirmary, Aberdeen, UK
1 3.9 Antrim Area Hospital, Antrim, UK
3 3.9 New Cross Hospital, Wolverhampton, UK
3 3.9 University Hospitals Monkland, Airdrie, UK
2 3.9 Basildon University Hospital, Essex, UK
1 4.0 Centre Hospitalier Sainte‐Anne, Paris, France
2 4.0 Craigavon Area Hospital, Portadown, UK
5 4.0 University Hospital, Cardiff, UK
1 4.0 Royal United Hospital Bath, Bath, UK
3 4.0 West Suffolk Hospital, Bury St Edmunds, UK
3 4.0 Derriford Hospital, Plymouth, UK
2 4.1 University Hospital of North Tees, Stockton on Tees, UK
1 4.1 Fairfield General Hospital, Bury, UK
1 4.2 Royal Preston Hospital, Preston, UK
1 4.3 Cheltenham General Hospital, Cheltenham, UK
1 4.5 Bradford Royal Infirmary, Bradford, UK
1 4.6 University Hospital of North Durham, Durham, UK
10 5.9 Kantonsspital St.Gallen, St. Gallen, Switzerland
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