TICH-3 trial
Tranexamic acid for IntraCerebral Haemorrhage 3


ISRCTN 97695350
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Room S/D2108, Stroke Trials Unit
School of Medicine, University of Nottingham
Queen's Medical Centre, Derby Road
Nottingham NG7 2UH, United Kingdom
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  • Serious Adverse Events (SAEs) — we have a legal responsibility to collect all safety events occurring within the first 7 days after randomisation (including SARs/SUSARs/fatal SAEs).
  • Safety events include: venous thromboembolism; ischaemic events (arterial thrombosis at any site, ischaemic stroke, transient ischaemic attack, peripheral artery embolism, myocardial infarction, acute coronary syndrome) and seizures.
  • Please remember that fatal SAEs need to be reported, even if after 7 days - unless death occurred after discharge from hospital.
  • Please assess if expected according to RSI.  Expectedness should only be assessed in events that are thought to be possibly/probably/definitely related to the IMP.
  • Investigators have a legal responsibility to report applicable SAEs to the chief investigator without delay, within 24 hours.

Latest recruiting hospitals
Aberdeen Royal Infirmary, Aberdeen, UK
Royal Derby Hospital, Derby, UK
Aarhus University Hospital, Aarhus, Denmark
Hospital UiTM, Selangor, Malaysia
Hôpital André Mignot, Le Chesnay, France
St. George's Hospital, London, UK
Helsinki University Hospital, Helsinki, Finland
Hospital Queen Elizabeth, Sabah, Malaysia
Royal Infirmary of Edinburgh, Edinburgh, UK
Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
Royal London Hospital, London, UK
Hospital Universitario de A Coruña, A Coruña, Spain
Kantonsspital St.Gallen, St. Gallen, Switzerland
James Cook University Hospital, Middlesbrough, UK
  
Average time to randomisation (last 6 months)
# Hours Hospital
5 2.0 Azienda Ospedalieria di Rilievo Nazionale Antonio Cardarelli, Napoli, Italy
1 2.0 Azienda USL Toscana Nord Ovest, Massa, Italy
19 2.0 Bispebjerg Hospital, Copenhagen, Denmark
7 2.0 Aalborg University Hospital, Gistrup, Denmark
2 2.1 Milton Keynes University Hospital, Milton Keynes, UK
4 2.3 Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
2 2.4 Royal Victoria Hospital, Belfast, UK
15 2.4 Helsinki University Hospital, Helsinki, Finland
10 2.5 Aarhus University Hospital, Aarhus, Denmark
5 2.6 CHU Lyon, Lyon, France
10 2.6 The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
14 2.6 Hospital Universitario de A Coruña, A Coruña, Spain
7 2.6 ASST Ovest Milanese, Legnano, Italy
4 2.6 Hospital UiTM, Selangor, Malaysia
1 2.6 Doncaster Royal Infirmary, Doncaster, UK
12 2.7 Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France
2 2.7 Addenbrooke's Hospital, Cambridge, UK
9 2.7 Northumbria Specialist Emergency Care Hospital, Northumberland, UK
3 2.7 Leeds General Infirmary, Leeds, UK
3 2.7 Hôpital Foch, Suresnes, France
2 2.8 Hospital Sultanah Aminah, Johor, Malaysia
3 2.8 Ipswich Hospital, Ipswich, UK
3 2.8 King's Mill Hospital, Sutton in Ashfield, UK
3 2.8 Norfolk and Norwich University Hospital, Norwich, UK
6 2.9 Hospital Universitari Vall d'Hebron, Barcelona, Spain
3 2.9 Royal Infirmary of Edinburgh, Edinburgh, UK
4 2.9 Royal London Hospital, London, UK
4 2.9 Royal Stoke University Hospital, Stoke-on-Trent, UK
4 2.9 Eastbourne General District Hospital, Eastbourne, UK
3 2.9 Southmead Hospital, Bristol, UK
2 3.0 Rigshospitalet, Copenhagen, Denmark
6 3.0 Presidio Ospedale San Carlo, Milano, Italy
4 3.0 Leicester Royal Infirmary, Leicester, UK
6 3.0 James Cook University Hospital, Middlesbrough, UK
2 3.0 Victoria Hospital, Kirkcaldy, UK
3 3.0 Whiston Hospital, Merseyside, UK
6 3.0 Hôpital Nord Laennec, Nantes, France
2 3.1 Southampton General Hospital, Southampton, UK
2 3.1 Royal Derby Hospital, Derby, UK
8 3.1 Aintree University Hospital, Liverpool, UK
2 3.1 York Hospital, York, UK
6 3.1 Hull Royal Infirmary, Hull, UK
12 3.1 St. George's Hospital, London, UK
4 3.1 Hôpital Pierre Paul Riquet, Toulouse, France
5 3.2 King's College Hospital, London, UK
4 3.2 Charing Cross Hospital, London, UK
4 3.2 Kent & Canterbury Hospital, Canterbury, Kent, UK
7 3.2 Hospital Queen Elizabeth II, Sabah, Malaysia
15 3.2 The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
4 3.3 Hospital Tengku Ampuan Rahimah, Selangor, Malaysia
1 3.3 University Hospital Hairmyres, East Kilbride, UK
7 3.3 Hospital Universitari de Girona Dr Josep Trueta, Girona, Spain
1 3.3 Royal Devon and Exeter Hospital, Exeter, UK
2 3.3 Hôpital Lariboisière, Paris, France
23 3.3 Hospital Queen Elizabeth, Sabah, Malaysia
1 3.3 Hospital Pengajar UPM, Serdang Selangor, Malaysia
2 3.3 Salford Royal Hospital, Salford, UK
8 3.3 Odense University Hospital, Odense, Denmark
2 3.4 Morriston Hospital, Swansea, UK
2 3.4 Watford General Hospital, Watford, UK
1 3.4 Royal Cornwall Hospital, Cornwall, UK
2 3.4 Royal Bournemouth Hospital, Bournemouth, UK
5 3.5 University Hospital, Cardiff, UK
5 3.5 Hôpital Pellegrin Bordeaux, Bordeaux, France
4 3.6 Hôpital André Mignot, Le Chesnay, France
4 3.6 Centre Hospitalier Sud Francilien, Paris, France
2 3.6 Peterborough City Hospital, Peterborough, UK
11 3.6 Hospital Sultanah Bahiyah, Kedah, Malaysia
5 3.6 Hospital Seberang Jaya, Pulau Pinang, Malaysia
3 3.6 Aberdeen Royal Infirmary, Aberdeen, UK
1 3.7 Queen's Hospital, Romford, UK
2 3.7 University Hospital of North Durham, Durham, UK
5 3.8 CHU Rouen, Rouen, France
1 3.8 Hospital Tuanku Jaafar, Seremban, Negeri Sembilan, Malaysia
2 3.8 Derriford Hospital, Plymouth, UK
2 3.8 Lincoln County Hospital, Lincoln, UK
2 3.8 Glan Clwyd Hospital, Denbighshire, UK
11 3.8 UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
1 3.8 Ninewells Hospital, Dundee, UK
6 3.9 Queen's Medical Centre, Nottingham, UK
1 3.9 Antrim Area Hospital, Antrim, UK
2 3.9 Basildon University Hospital, Essex, UK
1 4.0 Centre Hospitalier Sainte‐Anne, Paris, France
4 4.0 New Cross Hospital, Wolverhampton, UK
2 4.0 Craigavon Area Hospital, Portadown, UK
1 4.0 Royal United Hospital Bath, Bath, UK
3 4.0 West Suffolk Hospital, Bury St Edmunds, UK
2 4.1 University Hospital of North Tees, Stockton on Tees, UK
1 4.1 Hôpital Jean Minjoz, Besançon, France
1 4.1 ASST di Mantova, Mantova, Italy
1 4.1 Fairfield General Hospital, Bury, UK
2 4.2 University Hospitals Monkland, Airdrie, UK
1 4.2 Royal Preston Hospital, Preston, UK
1 4.3 Cheltenham General Hospital, Cheltenham, UK
1 4.3 Yeovil District Hospital, Somerset, UK
1 4.5 Bradford Royal Infirmary, Bradford, UK
11 5.7 Kantonsspital St.Gallen, St. Gallen, Switzerland
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