TICH-3 trial
Tranexamic acid for IntraCerebral Haemorrhage 3


ISRCTN 97695350
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Room S/D2108, Stroke Trials Unit
School of Medicine, University of Nottingham
Queen's Medical Centre, Derby Road
Nottingham NG7 2UH, United Kingdom
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  • Serious Adverse Events (SAEs) — we have a legal responsibility to collect all safety events occurring within the first 7 days after randomisation (including SARs/SUSARs/fatal SAEs).
  • Safety events include: venous thromboembolism; ischaemic events (arterial thrombosis at any site, ischaemic stroke, transient ischaemic attack, peripheral artery embolism, myocardial infarction, acute coronary syndrome) and seizures.
  • Please remember that fatal SAEs need to be reported, even if after 7 days - unless death occurred after discharge from hospital.
  • Please assess if expected according to SmPC  Expectedness should only be assessed in events that are thought to be possibly/probably/definitely related to the IMP.
  • Investigators have a legal responsibility to report applicable SAEs to the chief investigator without delay, within 24 hours.

Latest recruiting hospitals
Leeds General Infirmary, Leeds, UK
ASST di Mantova, Mantova, Italy
Southampton General Hospital, Southampton, UK
University Hospital of North Durham, Durham, UK
Hôpital André Mignot, Le Chesnay, France
New Cross Hospital, Wolverhampton, UK
ASST Ovest Milanese, Legnano, Italy
Charing Cross Hospital, London, UK
Hôpital Pierre Paul Riquet, Toulouse, France
James Cook University Hospital, Middlesbrough, UK
Queen Elizabeth Hospital Birmingham, Birmingham, UK
Aintree University Hospital, Liverpool, UK
Azienda Ospedalieria di Rilievo Nazionale Antonio Cardarelli, Napoli, Italy
UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
Royal Cornwall Hospital, Cornwall, UK
  
Average time to randomisation (last 6 months)
# Hours Hospital
31 2.1 Helsinki University Hospital, Helsinki, Finland
3 2.2 Azienda Ospedalieria di Rilievo Nazionale Antonio Cardarelli, Napoli, Italy
2 2.4 Doncaster Royal Infirmary, Doncaster, UK
2 2.4 Aintree University Hospital, Liverpool, UK
2 2.5 Royal United Hospital Bath, Bath, UK
22 2.6 Bispebjerg Hospital, Copenhagen, Denmark
10 2.6 LTD Pineo Medical Ecosystem, Tbilisi, Georgia
1 2.6 Princess Royal University Hospital, Orpington, UK
7 2.6 Royal Infirmary of Edinburgh, Edinburgh, UK
5 2.7 Salford Royal Hospital, Salford, UK
6 2.7 St. George's Hospital, London, UK
4 2.8 Aberdeen Royal Infirmary, Aberdeen, UK
3 2.8 Hospital Tuanku Jaafar, Seremban, Negeri Sembilan, Malaysia
7 2.8 The National Hospital for Neurology & Neurosurgery (UCLH), London, UK
2 2.8 Northumbria Specialist Emergency Care Hospital, Northumberland, UK
4 2.9 The Royal Victoria Infirmary, Newcastle Upon Tyne, UK
2 2.9 Ninewells Hospital, Dundee, UK
3 2.9 Leicester Royal Infirmary, Leicester, UK
1 2.9 University Hospitals Monkland, Airdrie, UK
7 2.9 Southampton General Hospital, Southampton, UK
9 2.9 Hôpital Roger Salengro, Lille, France
2 3.0 Musgrove Park Hospital, Taunton, UK
16 3.0 LEPL The First University Clinic of Tbilisi State, Tbilisi, Georgia
8 3.0 ASST Ovest Milanese, Legnano, Italy
1 3.0 Ipswich Hospital, Ipswich, UK
4 3.0 Hull Royal Infirmary, Hull, UK
17 3.1 UKM Medical Centre, Federal Territory Kuala Lumpur, Malaysia
6 3.1 Hospital Seberang Jaya, Pulau Pinang, Malaysia
3 3.1 Hôpital Foch, Suresnes, France
3 3.1 Southmead Hospital, Bristol, UK
1 3.1 Fairfield General Hospital, Bury, UK
2 3.1 South West Acute Hospital, County Fermanagh, UK
2 3.1 Kent & Canterbury Hospital, Canterbury, Kent, UK
9 3.1 Hospital Queen Elizabeth II, Sabah, Malaysia
3 3.2 Milton Keynes University Hospital, Milton Keynes, UK
4 3.2 Hospital Sultanah Bahiyah, Kedah, Malaysia
3 3.2 King's College Hospital, London, UK
20 3.2 Hospital Queen Elizabeth, Sabah, Malaysia
4 3.2 Victoria Hospital, Kirkcaldy, UK
4 3.2 Leeds General Infirmary, Leeds, UK
1 3.2 Bradford Royal Infirmary, Bradford, UK
4 3.2 Craigavon Area Hospital, Portadown, UK
13 3.2 Royal London Hospital, London, UK
3 3.3 New Cross Hospital, Wolverhampton, UK
7 3.3 Royal Stoke University Hospital, Stoke-on-Trent, UK
5 3.3 Royal Cornwall Hospital, Cornwall, UK
4 3.3 Hôpital André Mignot, Le Chesnay, France
3 3.4 Charing Cross Hospital, London, UK
6 3.4 Centre Hospitalier Sud Francilien, Paris, France
2 3.4 Sunderland Royal Hospital, Tyne and Wear, UK
4 3.5 Hospital Sultanah Nur Zahirah, Terengganu, Malaysia
4 3.5 Watford General Hospital, Watford, UK
1 3.5 Hospital Umum Sarawak, Sarawak, Malaysia
3 3.6 University Hospital of North Durham, Durham, UK
4 3.6 Royal Derby Hospital, Derby, UK
2 3.6 Darent Valley Hospital, Dartford, UK
3 3.6 Royal Preston Hospital, Preston, UK
3 3.7 Royal Victoria Hospital, Belfast, UK
8 3.7 Hôpital Pierre Paul Riquet, Toulouse, France
1 3.7 Hospital Sultanah Aminah, Johor, Malaysia
1 3.7 Hospital Universiti Sains Malaysia, Kelantan, Malaysia
1 3.7 Tallaght University Hospital, Dublin, Republic of Ireland
6 3.7 Addenbrooke's Hospital, Cambridge, UK
2 3.8 ASST di Mantova, Mantova, Italy
2 3.8 Arrowe Park Hospital, Wirral, UK
4 3.8 Hospital Tengku Ampuan Rahimah, Selangor, Malaysia
4 3.8 Luton and Dunstable University Hospital, Luton, UK
6 3.8 Queen Elizabeth Hospital Birmingham, Birmingham, UK
4 3.8 University Hospital of North Tees, Stockton on Tees, UK
4 3.9 Queen's Hospital, Romford, UK
2 3.9 Southend University Hospital, Essex, UK
2 3.9 Northwick Park Hospital, Harrow, UK
3 3.9 Queen's Medical Centre, Nottingham, UK
4 4.0 Yeovil District Hospital, Somerset, UK
2 4.0 Hôpital Jean Minjoz, Besançon, France
1 4.0 Hospital UiTM, Selangor, Malaysia
3 4.1 Countess of Chester Hospital, Chester, UK
1 4.1 Hospital Pengajar UPM, Serdang Selangor, Malaysia
2 4.1 Basildon University Hospital, Essex, UK
2 4.2 Hospital Kuala Lumpur, Kuala Lumpur, Malaysia
1 4.2 Royal Devon and Exeter Hospital, Exeter, UK
2 4.4 King's Mill Hospital, Sutton in Ashfield, UK
1 4.4 York Hospital, York, UK
2 4.5 James Cook University Hospital, Middlesbrough, UK
1 4.6 Royal Hallamshire Hospital, Sheffield, UK
1 5.0 Royal Berkshire Hospital, Berkshire, UK
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